Summary
Definition
History and exam
Key diagnostic factors
- presence of risk factors
- erythema or ulceration of oral mucosa
- oral pain
Risk factors
- intensive chemotherapy regimens
- radiotherapy to the oral cavity
- chemoradiation
- genetic polymorphisms in drug metabolic enzymes
Diagnostic investigations
Investigations to consider
- FBC and differential
- blood cultures
- superficial smear of lesion for microscopy
- fungal culture
- viral culture or PCR
Treatment algorithm
Contributors
Authors
Associate Professor
Associate Dean for Research
Section of Oral Medicine
University of Connecticut School of Dental Medicine
Farmington
CT
Disclosures
RVL serves as a consultant for Galera Therapeutics, Ingalfarma, Mundipharma and Sucampo Pharma, and has received research funding from Onxeo, Sucampo Pharma, Galera Therapeutics and Novartis.
Peer reviewers
Associate Chairman and Oral Medicine Residency Director
Department of Oral Medicine
Carolinas Medical Center
Charlotte
NC
Disclosures
MB is an author of a reference cited in this monograph. MB is part of the Mucositis Study Group of MASCC/ISOO, and participated in the review of mucositis.
Consultant Pediatric and Adolescent Oncologist
University College London Hospitals
London
UK
Disclosures
MM declares that she has no competing interests.
Use of this content is subject to our disclaimer