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瑞氏综合征

最后审阅: 23 Jun 2024
最后更新: 19 Apr 2023

小结

定义

病史和体格检查

关键诊断因素

  • 存在的危险因素
  • 呕吐
  • 精神状态改变
完整详情

其他诊断因素

  • 过度换气
  • 肝肿大
  • 瞳孔反应异常
  • 反射亢进/无反射
  • 疼痛反应减弱
  • 惊厥
  • 没有或极少黄疸和巩膜黄染
完整详情

危险因素

  • 5-14 岁
  • 白种人
  • 近期病毒性感染
  • 阿司匹林(乙酰水杨酸)及其他药物接触
  • 有遗传素质的个体
  • 毒素接触
  • 冬季/春季发病情况
完整详情

诊断性检查

首要检查

  • 血清电解质
  • 血清葡萄糖
  • 肝功能检查 (LFT)
  • 血清氨
  • PT/PTT
  • 尿液/血清毒理
  • 尿液分析
  • 血气
完整详情

需考虑的检查

  • 颅脑 CT
  • 腰椎穿刺和脑脊液分析
  • 脑电图 (EEG)
  • 肝脏活检
  • 代谢检测
完整详情

治疗流程

急症处理

所有患者

撰稿人

作者

Vanessa G. Carroll, MD, FAAP

Medical Director of Pediatric Hospital Medicine

Kootenai Health

Coeur d’Alene

ID

利益声明

VGC declares that she has no competing interests.

Russell W. Steele, MD, FAAP

Section Head of Pediatric Infectious Diseases

Ochsner Medical Center for Children

New Orleans

LA

利益声明

RWS declares that he has no competing interests.

鸣谢

Dr Vanessa G. Carroll and Dr Russell W. Steele would like to gratefully acknowledge Dr Barry M. Starr, a previous contributor to this topic. BMS declares that he has no competing interests.

同行评议者

William F. Balistreri, MD

Professor of Pediatrics

Cincinnati Children's Hospital Medical Center

Cincinnati

OH

利益声明

WFB declares that he has no competing interests.

Bernard Portmann, MD, FRCPath

Consultant Histopathologist

Institute of Liver Studies

King's College Hospital

London

UK

利益声明

BP declares that he has no competing interests.

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