Резюме
Определение
History and exam
Key diagnostic factors
- presença de fatores de risco
- sexo masculino com idade >40 anos
- dificuldades com atividades manuais
- nódulo palmar
- alterações na pele palmar
- cordas pré-tendinosas
- contratura da articulação metacarpofalângica
- contratura da articulação interfalangiana proximal (IFP)
- teste de Hueston positivo
Other diagnostic factors
- comprometimento bilateral
- nódulos de Garrod
- comprometimento da superfície plantar dos pés
- comprometimento do pênis
Risk factors
- sexo masculino
- idade >40 anos
- história familiar
- diabetes mellitus
- ingestão elevada de bebidas alcoólicas
- tabagismo
- trauma
- medicamentos anticonvulsivantes
Diagnostic investigations
Investigations to consider
- ultrassonografia da mão
Treatment algorithm
sem contraturas das articulações metacarpofalangianas ou interfalangianas proximais (IFP)
contraturas de ≤30 graus da articulação metacarpofalângica, sem contraturas da articulação interfalangiana proximal (IFP)
contraturas de >30 graus da articulação metacarpofalângica e/ou contraturas da articulação interfalangiana proximal (IFP)
Contributors
Authors
Craig M. Rodner, MD
Assistant Professor
Department of Orthopaedic Surgery
University of Connecticut Health Center/New England Musculoskeletal Institute
Farmington
CT
Disclosures
CMR declares that he has no competing interests.
Acknowledgements
Dr Craig M. Rodner would like to gratefully acknowledge Dr Thomas H. Trojian and Dr Daniel M. Avery, both previous contributors to this topic. THT and DMA declare that they have no competing interests.
Peer reviewers
Carlos Wigderowitz, MD, PhD, FRCSEd
Senior Clinical Lecturer in Orthopaedic and Trauma Surgery
Department of Orthopaedics and Trauma Surgery
TORT Centre
Ninewells Hospital
Dundee
UK
Disclosures
CW declares that he has no competing interests.
Bill Townley, MD
Specialist Registrar
Plastic Surgery
Salisbury District Hospital
Salisbury
UK
Disclosures
BT is an author of a reference cited in this topic.
Zhongyu Li, MD
Assistant Professor
Orthopaedics
Wake Forest University Baptist Medical Center
Winston-Salem
NC
Disclosures
ZL declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
Karbowiak M, Holme T, Khan K, et al. Dupuytren's disease. BMJ. 2021 Jun 4;373:n1308. Abstract
Boe C, Blazar P, Iannuzzi N. Dupuytren contractures: an update of recent literature. J Hand Surg Am. 2021 Oct;46(10):896-906.Full text Abstract
Ketchum LD, Donahue TK. The injection of nodules of Dupuytren's disease with triamcinolone acetonide. J Hand Surg Am. 2000 Nov;25(6):1157-62. Abstract
Badalamente MA, Hurst LC. Efficacy and safety of injectable mixed collagenase subtypes in the treatment of Dupuytren's contracture. J Hand Surg Am. 2007 Jul-Aug;32(6):767-74. Abstract
Hurst LC, Badalamente MA, Hentz VR, et al. Injectable collagenase clostridium histolyticum for Dupuytren's contracture. N Engl J Med. 2009 Sep 3;361(10):968-79.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

Differentials
- Dedo em gatilho
- Sarcoma epitelioide
- Camptodactilia
More DifferentialsGuidelines
- Dutch multidisciplinary guideline on Dupuytren disease
- Radiation therapy for early Dupuytren's disease
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