Última revisão: 30 Out 2020
Última atualização: 09 Jan 2020

Resumo

Definição

História e exame físico

Principais fatores de diagnóstico

  • presença de fatores de risco
  • febre
  • erupção cutânea
  • edema
  • volume de urina diminuído

Fatores de risco

  • uso de medicamentos desencadeantes
  • idade
  • doença inflamatória crônica

Exames diagnósticos

1° exames a serem solicitados

  • ureia e creatinina séricas
  • hemograma completo com diferencial de leucócitos
  • urinálise
  • teste de descontinuação do medicamento desencadeante
  • anticorpo anticitoplasma de neutrófilo (ANCA)
  • fator antinuclear (FAN)
  • anti-DNA de fita dupla (anti-ds DNA)
  • perfil complementar
Mais 1° exames a serem solicitados

Exames a serem considerados

  • ultrassonografia renal
  • biópsia renal
  • exame renal com gálio
  • citocinas na urina
Mais exames a serem considerados

Algoritmo de tratamento

Colaboradores

Professor of Medicine (Nephrology)

Section of Nephrology

Department of Internal Medicine

Yale School of Medicine

New Haven

CT

Divulgações

MAP declares that he has no competing interests.

Assistant Professor of Medicine (Nephrology)

Yale Program of Applied Translational Research

Department of Internal Medicine

Yale School of Medicine

New Haven

CT

Divulgações

DGM has received a grant from the National Institutes of Health (K23DK-117065), focusing on biomarkers of acute interstitial nephritis, and is supported by the Yale O'Brien Center, focusing on subclinical acute interstitial nephritis. He has a provisional patent application (co-inventor) for provisional patent number 62/716,465, "System and methods for diagnosing acute interstitial nephritis".

Prof. Mark A. Perazella and Dr Dennis G. Moledina would like to gratefully acknowledge Dr James Marsh, Dr Alice Appel, Dr Gerald Appel, and Dr Kate Shiell, previous contributors to this topic.

Divulgações

JM, AA, GA, and KS declare that they have no competing interests.

Colegas revisoresMOSTRAR TODOS

Assistant Professor

Chicago Medical School

Rosalind Franklin University

Lombard

IL

Divulgações

IM declares that he has no competing interests.

Associate Professor

Nephrologist

McMaster University

Hamilton

Ontario

Canada

Divulgações

CC declares that she has no competing interests.

Consultant Nephrologist/Lead Clinician

Renal Unit

Glasgow Royal Infirmary

NHS Greater Glasgow and Clyde

Glasgow

UK

Divulgações

RM declares that he has no competing interests.

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