Infecção por estreptococos do grupo B
Resumo
Определение
Анамнез и осмотр
Ключевые диагностические факторы
- presença de fatores de risco
- febre
- sintomas de meningite
- sinais de meningite
- sintomas da sepse
- sinais de sepse
- sintomas de pneumonia
- sinais de pneumonia
- sintomas de infecção do trato urinário
- sinais de infecção do trato urinário
- sintomas de celulite
- sinais de celulite
- sintomas de artrite séptica
- sinais de artrite séptica
- sintomas de conjuntivite
- sintomas de sinusite
- sinais de sinusite
- sintomas de otite média
- sinais de otite média
- sintomas de endometrite
- sinais de endometrite
- sinais de corioamnionite
Другие диагностические факторы
- sinais inespecíficos de infecção em neonatos
- sinais inespecíficos de infecção em idosos
- sintomas de infecção intra-abdominal
- sinais de infecção intra-abdominal
- aborto na metade da gestação ou trabalho de parto prematuro
Факторы риска
- 0 a 7 dias de idade
- febre materna durante o trabalho de parto
- ruptura prematura de membranas (RPM)
- bebê prévio com doença por EGB
- colonização materna por EGB
- bacteriúria por EGB durante a gestação
- parto prematuro (<37 semanas)
- baixo peso ao nascer (<2500 g)
- IgG materno específico deficiente no nascimento
- irmão gêmeo com doença por EGB
- idade materna <20 anos
- corioamnionite
- idade >60 anos
- gestação
- multiparidade
- diabetes
- obesidade
- doença hepática avançada
- doença renal
- presença de cateter venoso central
- distúrbios urológicos
- alteração da integridade da pele ou úlceras de pele
- doença neurológica
- imunossupressão
- residentes de casas de repouso
- raça negra ou hispânicos
- neoplasia maligna
- manipulação obstétrica
- presença de cateter urinário
- Infecção pelo vírus da imunodeficiência humana (HIV)
- trauma
- asma
- consumo de cápsulas de placenta
Диагностические исследования
Исследования, которые показаны в первую очередь
- Hemograma completo
- ureia sérica e creatinina
- eletrólitos séricos
- glicose sérica
- exames de coagulação
- TFHs
- proteína C-reativa
- hemocultura
- coloração de Gram do líquido cefalorraquidiano (LCR)
- cultura do LCR
- celularidade e diferencial do LCR
- glicose e proteína no LCR
- detecção de antígeno no LCR
- coloração de Gram e cultura de outros fluidos corporais estéreis
- radiografia torácica
- radiografia simples da articulação e/ou osso
- tomografia computadorizada (TC) do crânio
Исследования, проведение которых нужно рассмотреть
- ecocardiografia
- RNM
Алгоритм лечения
infecção neonatal por GBS confirmada de início precoce ou tardio (idade de 0-89 dias)
bebês e crianças
adultos: não gestantes
adultos: gestantes e pós-parto
Составители
Авторы
Brendan Healy, MBChB, BSc (Hons), MRCP, FRCPath
Consultant in Microbiology and Infectious Diseases
University Hospital of Wales
Cardiff
UK
Раскрытие информации
BH has received honorarium and has been reimbursed for attending conferences from AbbVie (hepatitis C), Gilead Sciences (hepatitis C), Bristol Myers Squibb (hepatitis C), and Tillotts Pharma (fidaxomicin). BH declares that he has no competing interests in relation to the work carried out for this topic review, Group B streptococcus.
Выражение благодарностей
Dr Brendan Healy would like to gratefully acknowledge Dr Susannah Froude and Dr Harriet Hughes, previous contributors to this topic. We would also like to gratefully acknowledge Dr Benjamin D. Lorenz for his contributions to this topic.
Раскрытие информации
SF declares that she has no competing interests. HH declares that she has received funds from Gilead and Biocomposites related to conference registration, travel, accommodation, and speaker fees.
Рецензенты
William A. Petri, Jr, MD, PhD, FACP
Chief and Professor of Medicine
Division of Infectious Diseases and International Health
University of Virginia Health System
Charlottesville
VA
Раскрытие информации
WAP declares that he has no competing interests.
James R. Hanley, MD, FAAP
Attending Physician
Pediatric Emergency Medicine
Ochsner Foundation Hospital
New Orleans
LA
Раскрытие информации
JRH declares that he has ownership of a limited amount of stock in various pharmaceutical companies, although no significant amounts of any company.
Kirsty Le Doare, BA, MBBS, MSc, PhD, FRCPCH
Professor of Vaccinology and Immunology
St George's, University of London
London
UK
Раскрытие информации
KLD declares that their institution has received funds for GBS vaccine clinical trials; she has not received personal funds.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Список литературы
Основные статьи
American Academy of Pediatrics. Group B streptococcal infections. In: Committee on Infectious Diseases, American Academy of Pediatrics, Kimberlin DW, Barnett ED, et al. Red book: 2021-2024 report of the Committee on Infectious Diseases. 32nd ed. Elk Grove Village, IL: AAP; 2021:707-13.
The American College of Obstetricians and Gynecologists. Prevention of group B streptococcal early-onset disease in newborns: ACOG Committee Opinion Summary, Number 797. Obstet Gynecol. 2020 Feb;135(2):489-92.Полный текст Аннотация
National Center for Health Statistics. Active bacterial core surveillance (ABCs) report: emerging infections program network - group B streptococcus, 2018 [internet publication].Полный текст
Royal College of Obstetricians and Gynaecologists. The prevention of early onset neonatal group B streptococcal disease. Green-top guideline no. 36. Sep 2017 [internet publication].Полный текст Аннотация
Ohlsson A, Shah VS. Intrapartum antibiotics for known maternal Group B streptococcal colonization. Cochrane Database Syst Rev. 2014 Jun 10;(6):CD007467.Полный текст Аннотация
Puopolo KM, Lynfield R, Cummings JJ, et al. Management of infants at risk for group B streptococcal disease. Pediatrics. 2019 Aug;144(2):e20191881.Полный текст Аннотация
American Society for Microbiology. Guidelines for the detection and identification of group B streptococcus. 29 July 2021 [internet publication].Полный текст
Статьи, указанные как источники
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Отличия
- Sepse causada por outros micro-organismos
- Endocardite causada por outros micro-organismos
- Infecção por citomegalovírus (CMV) neonatal
Больше ОтличияРекомендации
- Neonatal infection: antibiotics for prevention and treatment
- Guidelines for the detection and identification of group B streptococcus
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