Resumo
Definition
History and exam
Key diagnostic factors
- presença de fatores de risco
- febre
- diarreia e dor abdominal
- sintomas tipo gripe na gestação
Other diagnostic factors
- cefaleia
- estado mental alterado
- meningismo
- deficit dos nervos cranianos
- sinais cerebelares
- sinais neurológicos focais
- convulsões
- hipotensão
- mal-estar generalizado
- febre intraparto
- baixa aceitação alimentar (neonatos)
- diátese hemorrágica
- sopro cardíaco
Risk factors
- exposição a alimentos contaminados
- idade >45-50 anos
- gestação
- neonatos
- estados imunocomprometidos
- deficiência da acidificação do estômago
Diagnostic tests
1st tests to order
- Hemograma completo
- teste de gravidez na urina
- hemoculturas
- ressonância nuclear magnética (RNM) cranioencefálica
- tomografia computadorizada (TC) cerebral
- Análise do líquido cefalorraquidiano (LCR)
Tests to consider
- tempo de protrombina (TP) e TTP
- dímero D
- cultura da placenta e do líquido amniótico
- cultura de swab cervical
- coloração de Gram e cultura do mecônio
- sorologia de Listeria
- análise alimentar
- coprocultura
- Reação em cadeia da polimerase do sangue
- outras análises das fezes
- eletroencefalograma
- ecocardiografia
Treatment algorithm
gastroenterite
infecção sistêmica (excluindo meningite/meningoencefalite)
meningite/meningoencefalite
Contributors
Authors
Petros M. Karsaliakos, MD, FRCP, MSc
Honorary Clinical Senior Lecturer
Glasgow University
Consultant in General Medicine
Queen Elizabeth University Hospital
NHS GGC
Scotland
Disclosures
PMK declares that he has no competing interests.
Eleftherios Mylonakis, MD, PhD, FIDSA, FAAM
Charles C.J. Carpenter Professor of Infectious Disease
Chair, Department of Medicine
Charles and Anne Duncan Presidential Distinguished Chair
Professor of Medicine, Weill Cornell Medical College & Houston Methodist Academic Institute
Adjunct Professor of Medicine, Warren Alpert Medical School of Brown University
Adjunct Clinical Professor, Texas A&M College of Medicine
Houston Methodist Hospital
Houston, TX
Disclosures
EM is an author of several references cited in this topic.
Peer reviewers
Josiah D. Rich, MD, MPH
Professor of Medicine and Community Health
Brown University
Providence
RI
Disclosures
JDR declares that he has no competing interests.
Alistair Leonord, MBChB, BSc, MRCPath, MD, DTM&H
Professor
Infection and Immunity
Consultant Microbiologist
Bacteriology Dept
Southern General Hospital
Glasgow
UK
Disclosures
AL declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
Mylonakis E, Hofmann EL, Calderwood SB. Central nervous system infection with Listeria monocytogenes. 33 years' experience at a general hospital and review of 776 episodes from the literature. Medicine (Baltimore). 1998 Sep;77(5):313-36. Abstract
Quereda JJ, Morón-García A, Palacios-Gorba C, et al. Pathogenicity and virulence of listeria monocytogenes: a trip from environmental to medical microbiology. Virulence. 2021 Dec;12(1):2509-45.Full text Abstract
Committee on Obstetric Practice, American College of Obstetricians and Gynecologists. Committee opinion no. 614: management of pregnant women with presumptive exposure to listeria monocytogenes. Obstet Gynecol. 2014 Dec;124(6):1241-4. Abstract
Centers for Disease Control and Prevention. Listeria infection (listeriosis): clinical overview of listeriosis. Aug 2024 [internet publication].Full text
Osek J, Lachtara B, Wieczorek K. Listeria monocytogenes - how this pathogen survives in food-production environments? Front Microbiol. 2022;13:866462.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Outras meningites bacterianas
- Outros abscessos cerebrais
- Gastroenterite viral
More DifferentialsGuidelines
- Listeria (Listeriosis)
- Listeria infection (Listeriosis)
More Guidelines
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