Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- presença de fatores de risco
- febre
- sintomas constitucionais
- hiperemia conjuntival
- bradicardia relativa (sinal de Faget)
- enfermidade bifásica
- diátese hemorrágica
- sinais de insuficiência renal
- sinais de insuficiência hepática
- icterícia
Outros fatores diagnósticos
- hipotensão
- dor abdominal, vômitos e letargia
Fatores de risco
- residência ou viagem recente para uma área endêmica
- ausência de vacinação
- picada de mosquito
- viagens durante as estações chuvosas e no início das secas
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- Hemograma completo
- testes da função hepática
- coagulograma
- reação em cadeia da polimerase via transcriptase reversa (RT-PCR)
- sorologia
Investigações a serem consideradas
- eletrocardiograma (ECG)
- histopatologia
Novos exames
- isolamento viral
- teste de amplificação isotérmica de ácido nucleico
Algoritmo de tratamento
febre hemorrágica viral não identificada
febre amarela confirmada
Contributors
Authors
William A. Messer, MD, PhD
Associate Professor of Medicine
Department of Molecular Microbiology and Immunology
Division of Infectious Diseases
Oregon Health & Science University
Portland
PortlandOR
Disclosures
WAM declares that he has no competing interests.
Acknowledgements
Dr William A. Messer would like to gratefully acknowledge Dr Philip A. Yeon and Dr Helmut Albrecht, previous contributors to this topic.
Disclosures
PAY and HA declares that he has no competing interests.
Peer reviewers
Carlos Franco-Paredes, MD, MPH
Assistant Professor
Emory University
TravelWell Clinic
Emory University Hospital Midtown
Atlanta
GA
Disclosures
CFP declares that he has no competing interests.
Andrea K. Boggild, MSc, MD, DTMH, FRCPC
Clinical Assistant
Tropical Diseases Unit
Division of Infectious Diseases
Department of Medicine
Toronto General Hospital
University Health Network
Toronto
Canada
Disclosures
AKB declares that she has no competing interests.
References
Key articles
World Health Organization. Yellow fever: fact sheet. May 2023 [internet publication].Full text
Staples JE, Bocchini JA Jr, Rubin L; Centers for Disease Control and Prevention (CDC). Yellow fever vaccine booster doses: recommendations of the Advisory Committee on Immunization Practices, 2015. MMWR Morb Mortal Wkly Rep. 2015;64:647-650.Full text Abstract
Pan American Health Organization; World Health Organization. Laboratory diagnosis of yellow fever virus infection. September 2018 [internet publication].Full text
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Febre da dengue
- Malária
- Infecção pelo vírus da Zika
More DifferentialsGuidelines
- CDC Yellow Book: health information for international travel - yellow fever
- Yellow fever: the green book, chapter 35
More Guidelines
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