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Febre amarela

Última revisão: 18 Jun 2025
Última atualização: 10 Aug 2023

Resumo

Definición

Anamnesis y examen

Principales factores de diagnóstico

  • presença de fatores de risco
  • febre
  • sintomas constitucionais
  • hiperemia conjuntival
  • bradicardia relativa (sinal de Faget)
  • enfermidade bifásica
  • diátese hemorrágica
  • sinais de insuficiência renal
  • sinais de insuficiência hepática
  • icterícia
Todos los datos

Otros factores de diagnóstico

  • hipotensão
  • dor abdominal, vômitos e letargia
Todos los datos

Factores de riesgo

  • residência ou viagem recente para uma área endêmica
  • ausência de vacinação
  • picada de mosquito
  • viagens durante as estações chuvosas e no início das secas
Todos los datos

Pruebas diagnósticas

Primeras pruebas diagnósticas para solicitar

  • Hemograma completo
  • testes da função hepática
  • coagulograma
  • reação em cadeia da polimerase via transcriptase reversa (RT-PCR)
  • sorologia
Todos los datos

Pruebas diagnósticas que deben considerarse

  • eletrocardiograma (ECG)
  • histopatologia
Todos los datos

Pruebas emergentes

  • isolamento viral
  • teste de amplificação isotérmica de ácido nucleico

Algoritmo de tratamiento

Inicial

febre hemorrágica viral não identificada

Agudo

febre amarela confirmada

Colaboradores

Autores

William A. Messer, MD, PhD

Associate Professor of Medicine

Department of Molecular Microbiology and Immunology

Division of Infectious Diseases

Oregon Health & Science University

Portland

PortlandOR

Divulgaciones

WAM declares that he has no competing interests.

Agradecimientos

Dr William A. Messer would like to gratefully acknowledge Dr Philip A. Yeon and Dr Helmut Albrecht, previous contributors to this topic.

Disclosures

PAY and HA declares that he has no competing interests.

Revisores por pares

Carlos Franco-Paredes, MD, MPH

Assistant Professor

Emory University

TravelWell Clinic

Emory University Hospital Midtown

Atlanta

GA

Divulgaciones

CFP declares that he has no competing interests.

Andrea K. Boggild, MSc, MD, DTMH, FRCPC

Clinical Assistant

Tropical Diseases Unit

Division of Infectious Diseases

Department of Medicine

Toronto General Hospital

University Health Network

Toronto

Canada

Disclosures

AKB declares that she has no competing interests.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

World Health Organization. Yellow fever: fact sheet. May 2023 [internet publication].Full text

Staples JE, Bocchini JA Jr, Rubin L; Centers for Disease Control and Prevention (CDC). Yellow fever vaccine booster doses: recommendations of the Advisory Committee on Immunization Practices, 2015. MMWR Morb Mortal Wkly Rep. 2015;64:647-650.Full text  Abstract

Pan American Health Organization; World Health Organization. Laboratory diagnosis of yellow fever virus infection. September 2018 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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    • CDC Yellow Book: health information for international travel - yellow fever
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