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Síndrome respiratória aguda grave (SARS)

Última revisão: 17 Jul 2025
Última atualização: 10 Feb 2022

Resumo

Definição

História e exame físico

Principais fatores diagnósticos

  • presença de fatores de risco
  • febre
  • tosse
  • mialgia
  • dispneia
Detalhes completos

Outros fatores diagnósticos

  • calafrios
  • mal-estar
  • cefaleia
  • diarreia aquosa
  • taquipneia
  • taquicardia
  • cianose
  • náuseas e vômitos
  • faringite
  • produção de escarro
  • dor torácica
  • pleurisia
  • rinorreia
  • tontura
  • artralgia
  • dor abdominal
  • convulsão
  • delirium
  • estertores
  • estertores inspiratórios
  • sopro tubário
Detalhes completos

Fatores de risco

  • viagem para uma área afetada
  • contato próximo com uma pessoa infectada
  • trabalho laboratorial com SARS-CoV
Detalhes completos

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • Hemograma completo
  • aminotransferases
  • lactato desidrogenase
  • creatina quinase
  • hemocultura
  • cultura de escarro
  • culturas virais nasofaríngeas
  • coloração para anticorpo por imunofluorescência direta
  • radiografia torácica
  • oximetria de pulso
  • reação em cadeia da polimerase via transcriptase reversa (RT-PCR)
Detalhes completos

Investigações a serem consideradas

  • gasometria arterial
  • coagulograma
  • tomografia computadorizada de alta resolução (TCAR) do tórax
  • teste sorológico para anticorpos específicos para SARS-CoV
  • cultura viral
Detalhes completos

Novos exames

  • imunoensaio rápido com swab para detecção de SARS-CoV
  • anticorpos monoclonais

Algoritmo de tratamento

Inicial

suspeita de síndrome respiratória aguda grave (SARS)

AGUDA

síndrome respiratória aguda grave (SARS) confirmada

Colaboradores

Autores

Georgia G. Pitsiou, MD, PhD
Georgia G. Pitsiou

Associate Professor in Pulmonary Medicine

Aristotle University of Thessaloniki

Respiratory Failure Clinic

General Hospital G. Papanikolaou

Thessaloniki

Greece

Declarações

GGP declares that she has no competing interests.

Ioannis P. Kioumis, MD, PhD
Ioannis P. Kioumis

Professor in Pulmonary Medicine

Infectious Diseases

Aristotle University of Thessaloniki

Respiratory Failure Clinic

General Hospital G. Papanikolaou

Thessaloniki

Greece

Declarações

IPK declares that he has no competing interests.

Revisores

Tommy R. Tong, MD

Attending Pathologist

Montefiore Medical Center

Bronx

NY

Disclosures

TRT declares that he has no competing interests.

Sian Griffiths, OBE, MA, MB BChir, FFPHM, FRCP (Lon), FRCP (Edin), FHKCCM

Director of the School of Public Health

Chinese University of Hong Kong

Prince of Wales Hospital

New Territories

Hong Kong

Disclosures

SG declares that she has no competing interests.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Christian MD, Poutanen SM, Loutfy MR, et al. Severe acute respiratory syndrome. Clin Infect Dis. 2004;38:1420-1427.Full text  Abstract

Peiris JS, Chu CM, Cheng VC, et al. Clinical progression and viral load in a community outbreak of coronavirus-associated SARS pneumonia: a prospective study. Lancet. 2003;361:1767-1772. Abstract

Mahony JB, Richardson S. Molecular diagnosis of severe acute respiratory syndrome: the state of the art. J Mol Diagn. 2005;7:551-559. Abstract

Peiris JS, Yuen KY, Osterhaus AD, et al. The severe acute respiratory syndrome. N Engl J Med. 2003;349:2431-2441. Abstract

Fowler RA, Lapinsky SE, Hallet D, et al. Critically ill patients with severe acute respiratory syndrome. JAMA. 2003;290:367-373.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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