Última revisão: 27 Jun 2021
Última atualização: 22 GUA 2018

Resumo

Diagnósticos diferenciais

comuns

  • Sepse
  • Tifoide
  • Brucelose
  • vírus da imunodeficiência humana (HIV)
  • Hepatite
  • Gripe (influenza)
  • Mononucleose infecciosa
  • Vírus sincicial respiratório
  • Eritema infeccioso
  • Rickettsia
  • Induzida por medicamentos
  • Quimioterapia citotóxica
  • Radioterapia
  • Neutropenia imune
  • Leucemia mielogênica aguda
  • Leucemia linfocítica aguda
  • Síndrome mielodisplásica
  • Leucemia linfocítica crônica (LLC)
  • Linfoma de Hodgkin
  • Linfoma não Hodgkin
  • Infiltração por malignidade secundária
  • Anemia aplásica
  • Deficiência de vitamina B12/folato
  • Abuso de álcool

Incomuns

  • Citomegalovírus
  • Rubéola
  • Sarampo
  • Varicela
  • Erliquiose granulocítica humana
  • Malária
  • Leishmaniose
  • Reação transfusional
  • Deficiência de cobre
  • Artrite reumatoide
  • Lúpus eritematoso sistêmico
  • Síndrome de Sjögren
  • Síndrome de Felty
  • Marginação de neutrófilos elevada
  • Desvio laboratorial
  • Síndromes de falência medular
  • Síndromes de neutropenia isolada
  • Síndromes de imunodeficiência
  • Erros inatos do metabolismo

Colaboradores

Autores

Edward Copelan, MD, FACP

Chairman

Department of Hematologic Oncology and Blood Disorders

Levine Cancer Institute

Carolinas HealthCare System

Charlotte

NC

Declarações

EC declares that he has no competing interests.

Belinda Avalos, MD

Vice-Chair

Department of Hematologic Oncology and Blood Disorders

Levine Cancer Institute

Carolinas HealthCare System

Charlotte

NC

Declarações

BA declares that she has no competing interests.

Reed Friend, MD

Fellow

Hematologic Oncology and Blood Disorders

Levine Cancer Institute

Carolinas HealthCare System

Charlotte

NC

Declarações

RF has been reimbursed by Amgen and Takeda Oncology for serving on the speakers' bureau for carfilzomib, xgeva, and ixazomib.

Agradecimentos

Dr Edward Copelan, Dr Belinda Avalos, and Dr Reed Friend would like to gratefully acknowledge Dr Lisa Sproat, the previous contributor to this topic. LS declares that she has no competing interests.

Revisores

Sally E. Kinsey, MD, FRCP, FRCPath, FRCPCH

Professor of Paediatric Haematology

University of Leeds and Leeds Teaching Hospitals NHS Trust

St. James's University Hospital

Leeds

UK

Declarações

SEK is a medical advisory board member of the Severe Chronic Neutropenia International Registry (not remunerated) and is an author of references cited in the topic including data from the registry. SEK has been in receipt of educational grants from Chugai Pharma.

Laurence A. Boxer, MD

Professor

Pediatric Hematology/Oncology

Associate Chair

Department of Pediatrics and Communicable Diseases

Henry and Mala Dorfman Family Professorship

Pediatric Hematology/Oncology

Ann Arbor

MI

Declarações

LAB is an author of references cited in this topic. LAB declares that he has no competing interests.

Cornelia Zeidler, MD

SCNIR

DCC Europe

Medizinische Hochschule Hannover

Kinderklinik

Hannover

Germany

Declarações

Not disclosed.

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