Última revisão: 1 Fev 2021
Última atualização: 26 Jun 2020

Resumo

Definição

História e exame físico

Principais fatores diagnósticos

  • lesões edematosas eritematosas
  • prurido
  • resolução em 24 horas
  • inchaço da face, língua ou lábios

Fatores de risco

  • história familiar positiva
  • sexo feminino
  • exposição a medicamento desencadeante
  • exposição a alimento desencadeante
  • infecção viral recente
  • ferroada ou picada de inseto recente

Investigações diagnósticas

Primeiras investigações a serem solicitadas

  • Hemograma completo com diferencial
  • velocidade de hemossedimentação (VHS)
  • proteína C-reativa
  • nível de C4

Investigações a serem consideradas

  • hormônio estimulante da tireoide (TSH)
  • fatores antinucleares (FANs)
  • teste alérgico cutâneo por puntura ("prick test")
  • dieta para evitar alérgenos
  • triptase sérica
  • biópsia de pele
  • nível de inibidor de C1 esterase
  • função do inibidor de C1 esterase
  • níveis de C1q
  • IgE específica para alérgeno suspeito

Algoritmo de tratamento

Colaboradores

Professor of Medicine

Department of Internal Medicine

Division of Immunology/Allergy Section

University of Cincinnati

Cincinnati

OH

Declarações

JB is a consultant, contracted researcher, and speaker for Sanofi-Regeneron, AstraZeneca, Novartis/Regeneron, Shire/Takeda, CSL Behring, Pharming. He is also a consultant and contracted researcher for Allakos, Kalvista, Bioscryst, IONIS. JB is a member of the Joint Task Force practice parameter. JB has spoken on this topic at National, International and Regional/Local Educational meetings. JB is an author of abstracts and manuscripts related to these topics and is an author of a number of references cited in this topic.

Dr Jonathan Bernstein would like to gratefully acknowledge Dr S. Shahzad Mustafa and Dr Stephen Dreskin, previous contributors to this topic.

Declarações

SM is on the speakers' panel and advisory board for Genentech. SD declares that he has no competing interests.

RevisoresVER TUDO

Consultant Dermatologist

Warwick Hospital

Honorary Associate Professor

University of Warwick

Warwick Hospital

Warwick

UK

Declarações

FH has attended educational events organised and funded by Almrall and Schering Plough; has received a speaker's fee from Steibel, Leo, and Schering Plough; and is an author of references cited in this topic.

Consultant in Dermatology

University Hospital of South Manchester

Manchester

UK

Declarações

None declared.

Head of Allergy and Training Program Director

Winthrop University Hospital

Associate Professor of Clinical Medicine

SUNY at Stony Brook

Stony Brook

NY

Declarações

LF declares that she has no competing interests.

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