Summary
Differentials
Common
- Alergia medicamentosa ou alimentar
- Picadas ou ferroadas de insetos
- Reação adversa ao medicamento (por exemplo, a antibiótico, anticonvulsivante ou alopurinol)
- Quimioterapia
- Infecção por enterovírus e ecovírus
- Quinta doença (eritema infeccioso)
- Roséola infantum (sexta doença)
- Infecção pelo vírus Epstein-Barr (EBV) (mononucleose infecciosa)
- Infecção por citomegalovírus (CMV)
Uncommon
- Reação adversa não imediata a meio de contraste iodado
- Necrólise epidérmica tóxica/síndrome de Stevens-Johnson
- Reação ao medicamento acompanhada de eosinofilia e sintomas sistêmicos
- Eritema multiforme
- Exantema de soroconversão para HIV (também conhecido como síndrome retroviral aguda)
- Varíola símia
- Sepse
- Infecção aguda pelo vírus da hepatite B
- Infecção aguda pelo vírus da hepatite C
- Rubéola (sarampo alemão)
- Rubéola (sarampo)
- Meningococcemia
- Escarlatina
- Síndrome da pele escaldada estafilocócica
- Síndrome do choque tóxico (exotoxina de Staphylococcus)
- Febre maculosa das Montanhas Rochosas ou febre maculosa do Mediterrâneo
- Doença do enxerto contra o hospedeiro (DECH) aguda
- Doença de Kawasaki (síndrome do linfonodo mucocutâneo)
- Doença de Still do jovem ou do adulto
- Sífilis (secundária)
- Doença do Ebola
- Infecção pelo vírus da Zika
- Infecção pelo vírus da chikungunya
- Febre da dengue
Contributors
Authors
Adelaide A. Hebert, MD
Professor & Director of Pediatric Dermatology
Department of Dermatology and Pediatrics
UTHealth McGovern Medical School Houston
Houston
TX
Disclosures
AAH has received research grants paid to UTHealth McGovern Medical School Houston from Pfizer, GlaxoSmithKline (GSK), Novan, Dermavant, Arcutis, and Verrica; has received honoraria from Pfizer, Verrica, and Novan; and is on data safety monitoring boards for GSK, Ortho Dermatologics, and Regeneron-Sanofi.
Yamila Goenaga, MD
Dermatology Resident
Department of Dermatology
University of Texas Health Sciences Center in Houston
Houston
TX
Disclosures
YG declares that she has no competing interests.
Alexander J. Jafari, MD, MPH
Clinical Research Fellow
Department of Dermatology
UTHealth McGovern Medical School Houston
Houston
TX
Disclosures
AJJ declares that he has no competing interests.
Acknowledgements
Dr Adelaide A. Hebert, Dr Yamila Goenaga, and Dr. Alexander Jafari would like to gratefully acknowledge Dr Quoc-Bao Nguyen, Dr Mary DarConte, Dr Mark Naftanel, and Dr Hobart W. Walling, previous contributors to this topic.
Disclosures
QN, MD, MN, and HWW declare that they have no competing interests.
Peer reviewers
Brian Swick, MD
Clinical Assistant Professor
University of Iowa College of Medicine
Iowa City
IA
Disclosures
BS declares that he has no competing interests.
Kimberly Schulz, MD
Dermatologist
Town Square Dermatology
Coralville
IA
Disclosures
KS declares that she has no competing interests.
References
Key articles
Resuscitation Council UK. Emergency treatment of anaphylactic reactions: guidelines for healthcare providers. May 2021 [internet publication].Full text
Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology, et al. Drug allergy: an updated practice parameter. Ann Allergy Asthma Immunol. 2010 Oct;105(4):259-73. Abstract
McCrindle BW, Rowley AH, Newburger JW, et al. Diagnosis, treatment, and long-term management of Kawasaki disease: a scientific statement for health professionals from the American Heart Association. Circulation. 2017 Apr 25;135(17):e927-99.Full text Abstract
Khan DA, Banerji A, Blumenthal KG, et al. Drug allergy: a 2022 practice parameter update. J Allergy Clin Immunol. 2022 Dec;150(6):1333-93.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Guidelines
- Diagnostic testing for Ebola and Marburg virus diseases: interim guidance, 20 December 2024
- Update on diagnosis and management of kawasaki disease: a scientific statement from the American Heart Association
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