Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- menos de 2 anos de idade
- imunossupressão
- febre alta
- exantema
Outros fatores diagnósticos
- diarreia
- dor abdominal
- manchas de Nagayama
- inflamação na membrana timpânica
- sintomas no trato respiratório superior
- convulsões
- edema periorbital
- fontanela anterior abaulada
- linfadenopatia cervical, occipital ou pós-auricular
Fatores de risco
- menos de 2 anos de idade
- imunossupressão
Investigações diagnósticas
Primeiras investigações a serem solicitadas
- nenhum exame inicial
Investigações a serem consideradas
- cultura viral
- detecção de anticorpo
Novos exames
- reação em cadeia da polimerase
- imuno-histoquímica
Algoritmo de tratamento
todos os pacientes
Colaboradores
Autores
Henry M. Feder, Jr., MD
Professor of Pediatrics and Family Medicine
University of Connecticut Medical Center and Connecticut Children’s Medical Center
Farmington
CT
Declarações
HMF declares that he has no competing interests.
Hassan El Chebib, MD
Attending Physician in the Division of Infectious Diseases and Immunology
Connecticut Children’s Medical Center
Assistant Professor of Pediatrics
Pediatrics, Infectious Diseases and Immunology
University of Connecticut School of Medicine
Hartford
CT
Declarações
HEC declares that he has no competing interests.
Ashley C. Howard, DO
Attending Physician in the Division of Infectious Diseases and Immunology
Connecticut Children’s Medical Center
Assistant Professor of Pediatrics
Pediatrics, Infectious Diseases and Immunology
University of Connecticut School of Medicine
Hartford
CT
Disclosures
ACH declares that she has no competing interests.
Acknowledgements
Dr Henry M. Feder, Dr Hassan El Chebib, and Dr Ashley C. Howard would like to gratefully acknowledge Dr Edward C. Kim, Dr Nicholas Bennett, Dr James Azim, Dr Margie C. Andreae, Dr Jon Dyer, and Dr Jennifer Holman, the previous contributors to this topic.
Disclosures
ECK, NB, JA, MCA, JD, and JH declare that they have no competing interests.
Peer reviewers
Helen Goodyear, MBChB, MRCP, FRCPCH, MD, MMed
Consultant Paediatrician
Heartlands Hospital
Birmingham
UK
Disclosures
HG declares that she has no competing interests.
Mary T. Caserta, MD
Associate Professor of Pediatrics
Department of Pediatrics
Division of Infectious Diseases
University of Rochester Medical Center
Rochester
NY
利益声明
MTC declares that she has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
参考文献
关键文献
Kimberlin DW, Barnett ED, Lynfield R, et al. Human herpesvirus 6 (including roseola) and 7. In: Red Book: 2021–2024 report of the Committee on Infectious Diseases. 32nd ed. Itasca, IL: American Academy of Pediatrics; 2021.
Hall CB, Long CE, Schnabel KC, et al. Human herpesvirus-6 infection in children: a prospective study of complications and reactivation. N Engl J Med. 1994 Aug 18;331(7):432-8.全文 摘要
参考文献
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
鉴别诊断
- Sarampo
- Enterovírus
- Vírus Epstein-Barr
更多 鉴别诊断指南
- Viral exanthems
- Human herpesvirus 6 (including roseola) and 7
更多 指南
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