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Roséola

  • Overview
  • Theory
  • Diagnosis
  • Management
  • Follow up
  • Resources
Last reviewed: 19 Jun 2025
Last updated: 26 Oct 2022

Summary

Definition

History and exam

Key diagnostic factors

  • menos de 2 anos de idade
  • imunossupressão
  • febre alta
  • exantema
Full details

Other diagnostic factors

  • diarreia
  • dor abdominal
  • manchas de Nagayama
  • inflamação na membrana timpânica
  • sintomas no trato respiratório superior
  • convulsões
  • edema periorbital
  • fontanela anterior abaulada
  • linfadenopatia cervical, occipital ou pós-auricular
Full details

Risk factors

  • menos de 2 anos de idade
  • imunossupressão
Full details

Diagnostic tests

1st tests to order

  • nenhum exame inicial
Full details

Tests to consider

  • cultura viral
  • detecção de anticorpo
Full details

Emerging tests

  • reação em cadeia da polimerase
  • imuno-histoquímica

Treatment algorithm

ACUTE

todos os pacientes

Contributors

Authors

Henry M. Feder, Jr., MD

Professor of Pediatrics and Family Medicine

University of Connecticut Medical Center and Connecticut Children’s Medical Center

Farmington

CT

Disclosures

HMF declares that he has no competing interests.

Hassan El Chebib, MD

Attending Physician in the Division of Infectious Diseases and Immunology

Connecticut Children’s Medical Center

Assistant Professor of Pediatrics

Pediatrics, Infectious Diseases and Immunology

University of Connecticut School of Medicine

Hartford

CT

Disclosures

HEC declares that he has no competing interests.

Ashley C. Howard, DO

Attending Physician in the Division of Infectious Diseases and Immunology

Connecticut Children’s Medical Center

Assistant Professor of Pediatrics

Pediatrics, Infectious Diseases and Immunology

University of Connecticut School of Medicine

Hartford

CT

Disclosures

ACH declares that she has no competing interests.

Acknowledgements

Dr Henry M. Feder, Dr Hassan El Chebib, and Dr Ashley C. Howard would like to gratefully acknowledge Dr Edward C. Kim, Dr Nicholas Bennett, Dr James Azim, Dr Margie C. Andreae, Dr Jon Dyer, and Dr Jennifer Holman, the previous contributors to this topic.

Disclosures

ECK, NB, JA, MCA, JD, and JH declare that they have no competing interests.

Peer reviewers

Helen Goodyear, MBChB, MRCP, FRCPCH, MD, MMed

Consultant Paediatrician

Heartlands Hospital

Birmingham

UK

Disclosures

HG declares that she has no competing interests.

Mary T. Caserta, MD

Associate Professor of Pediatrics

Department of Pediatrics

Division of Infectious Diseases

University of Rochester Medical Center

Rochester

NY

Disclosures

MTC declares that she has no competing interests.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Kimberlin DW, Barnett ED, Lynfield R, et al. Human herpesvirus 6 (including roseola) and 7. In: Red Book: 2021–2024 report of the Committee on Infectious Diseases. 32nd ed. Itasca, IL: American Academy of Pediatrics; 2021.

Braun DK, Dominguez G, Pellett PE. Human herpesvirus 6. Clin Microbiol Rev. 1997;10:521-67.Full text  Abstract

Hall CB, Long CE, Schnabel KC, et al. Human herpesvirus-6 infection in children: a prospective study of complications and reactivation. N Engl J Med. 1994 Aug 18;331(7):432-8.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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