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Meduloblastoma

  • Обзор
  • Теория
  • Диагноз
  • Лечение
  • Последующее наблюдение
  • Источники
Последний просмотренный: 15 Oct 2026
Last updated: 22 Oct 2025

Резюме

Определение

Анамнез и осмотр

Ключевые диагностические факторы

  • cefaleia
  • náuseas e vômitos
Полная информация

Другие диагностические факторы

  • alterações comportamentais
  • diplopia
  • oftalmoplegias
  • fontanela anterior abaulada
  • papiledema
  • nistagmo
  • inclinação da cabeça
  • ataxia
  • dismetria
  • letargia
Полная информация

Факторы риска

  • idade entre 1 e 9 anos
  • sexo masculino
  • síndromes familiares hereditárias associadas
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • ressonância nuclear magnética (RNM) cranioencefálica
  • tomografia computadorizada (TC) cerebral
  • histologia
  • RNM da coluna cervical, torácica e lombar
  • punção lombar
  • ressonância nuclear magnética (RNM) pós-operatória
Полная информация

Алгоритм лечения

Острый

idade <3 anos

≥3 anos de idade

Составители

Авторы

Tobey J. MacDonald, MD

Professor

Department of Pediatrics

Emory University School of Medicine

Atlanta

GA

Раскрытие информации

TJM declares that he has no competing interests.

Выражение благодарностей

Dr Tobey J. MacDonald would like to gratefully acknowledge Dr Gail Horan, Dr Fiona Harris, Dr Thankamma V. Ajithkumar, Dr Sindu Vivekanandan, Dr Barry Pizer, Dr Michael J. Fisher, Dr Phillip B. Storm, and Dr Gregory G. Heuer, the previous contributors to this topic.

Disclosures

GH carries out lectures and paid consultancy work for Janssen, and holds shares in GenesisCare. GH and TVA are authors of references cited in this topic. FH, SV, BP, MJF, PBS, and GGH declare that they have no competing interests.

Peer reviewers

David Rowed, MD

Division of Neurosurgery

University of Toronto

Toronto

Ontario

Canada

Disclosures

DR declares that he has no competing interests.

Michael Vloeberghs, MD, PhD

Professor of Paediatric Neurosurgery

Nottingham University Hospital

Nottingham

UK

Disclosures

MV declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: pediatric central nervous system cancers [internet publication].Full text

Louis DN, Perry A, Wesseling P, et al. The 2021 WHO classification of tumors of the central nervous system: a summary. Neuro Oncol. 2021 Aug 2;23(8):1231-51.Full text  Abstract

Franceschi E, Hofer S, Brandes AA, et al. EANO-EURACAN clinical practice guideline for diagnosis, treatment, and follow-up of post-pubertal and adult patients with medulloblastoma. Lancet Oncol. 2019 Dec;20(12):e715-28. Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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