Summary
Definition
History and exam
Key diagnostic factors
- presença de fatores de risco
- cefaleia
- deficit neurológico
- convulsão
Other diagnostic factors
- deficit cognitivo
- vertigens/tonturas
Risk factors
- radiação ionizante
- predisposição genética
- hormônios: endógenos ou exógenos
- trauma cranioencefálico
Diagnostic tests
1st tests to order
- RNM cranioencefálica ou da coluna com e sem contraste
Tests to consider
- TC cranioencefálica ou da coluna vertebral
- PET/TC com receptores da somatostatina
- angiografia cerebral
- histopatologia de ressecção cirúrgica
Treatment algorithm
bom candidato cirúrgico
não candidato à cirurgia
tumor recorrente ou progressivo após o tratamento inicial
Contributors
Authors
Stephen T. Magill, MD, PhD
Assistant Professor
Lou and Jean Malnati Brain Tumor Institute
Robert Lurie Comprehensive Cancer Center
Department of Neurological Surgery
Northwestern University Feinberg School of Medicine
Chicago
IL
Disclosures
STM has authored several articles cited in this topic.
Acknowledgements
Dr Stephen T. Magill would like to gratefully acknowledge Professor William T. Couldwell and Dr Jayson A. Neil, previous contributors to this topic.
Disclosures
WTC is an author of several references cited in this topic. JAN declares that he has no competing interests.
Peer reviewers
Marc Chamberlain, MD
Professor of Neurology
Moffitt Cancer Center and Research Institute
University of Washington
Seattle
WA
Disclosures
MC is an author of several references cited in this topic.
Ian McCutcheon, MD
Professor of Neurosurgery
The University of Texas M. D. Anderson Cancer Center
Houston
TX
Disclosures
IM declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
World Health Organization Classification of Tumours Editorial Board. WHO classification of tumours of the central nervous system. 5th Edition. France: IARC; 2021.
Louis DN, Perry A, Wesseling P, et al. The 2021 WHO Classification of Tumors of the Central Nervous System: a summary. Neuro Oncol. 2021 Aug 2;23(8):1231-51.Full text Abstract
National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: central nervous system cancers [internet publication].Full text
Goldbrunner R, Stavrinou P, Jenkinson MD, et al. EANO guideline on the diagnosis and management of meningiomas. Neuro Oncol. 2021 Nov 2;23(11):1821-34.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Metástase dural
- Granuloma
- Doença relacionada à IgG4
More DifferentialsGuidelines
- Suspected cancer: recognition and referral
- NCCN guidelines: central nervous system cancers
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