Resumo
Definição
História e exame físico
Principais fatores diagnósticos
- presença de fatores de risco
- febre baixa
- vesículas e úlceras orais
- erupção cutânea e/ou vesículas nas mãos e pés
Outros fatores diagnósticos
- mal-estar
- ferida na boca
- perda de apetite
- faringite
- erupção cutânea e/ou vesículas nas nádegas
- dor abdominal
- diarreia
- tosse
- eritema/edema na língua
- artralgia
Fatores de risco
- imunossupressão
- idade <10 anos
- contatos na família ou na escola com infecção
Investigações diagnósticas
Investigações a serem consideradas
- cultura viral
- Hemograma completo
Novos exames
- ensaios moleculares por reação em cadeia da polimerase
Algoritmo de tratamento
todos os pacientes
Colaboradores
Autores
Malobi I. Ogboli, MBBS, FRCP
Consultant Dermatologist
Birmingham Children's Hospital and Birmingham City Hospital
Birmingham
UK
Declarações
MIO declares that she has no competing interests.
Revisores
Helen Goodyear, MBChB, MRCP, FRCPCH, MD, MMed
Consultant Paediatrician
Heartlands Hospital
Birmingham
UK
Declarações
HG declares that she has no competing interests.
Andrew Riordan, MD, FRCPCH, MRCP, DTM&H
Consultant in Paediatric Infectious Diseases and Immunology
Royal Liverpool Children's Hospital (Alder Hey)
Liverpool
UK
Declarações
AR declares that he has no competing interests.
David Cassarino, MD, PhD
Assistant Professor
Department of Pathology and Laboratory Medicine
University of California
Los Angeles
CA
Declarações
DC declares that he has no competing interests.
Leonid Izikson, MD
Staff Dermatologist
Department of Dermatology
Massachusetts General Hospital
Boston
MA
Declarações
LI declares that he has no competing interests.
Aisha Sethi, MD
Assistant Professor of Medicine
Associate Residency Program Director
University of Chicago
Chicago
IL
Declarações
AS declares that she has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Referências
Principais artigos
Alsop J, Flewett TH, Foster JR. "Hand-foot-and-mouth disease" in Birmingham in 1959. Br Med J. 1960;2:1708-1711.Texto completo Resumo
Ishimaru Y, Nakano S, Yamaoka K, et al. Outbreaks of hand, foot, and mouth disease by enterovirus 71. High incidence of complication disorders of central nervous system. Arch Dis Child. 1980;55:583-588.Texto completo Resumo
Saguil A, Kane SF, Lauters R, et al. Hand-foot-and-mouth disease: rapid evidence review. Am Fam Physician. 2019 Oct 1;100(7):408-14.Texto completo Resumo
Chang LY, Tsao KC, Hsia SH, et al. Transmission and clinical features of enterovirus 71 infections in household contacts in Taiwan. JAMA. 2004;291:222-227.Texto completo Resumo
Chang LY, Lin TY, Huang YC, et al. Comparison of enterovirus 71 and coxsackie-virus A16 clinical illnesses during the Taiwan enterovirus epidemic, 1998. Pediatr Infect Dis J. 1999;18:1092-1096. Resumo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
Diagnósticos diferenciais
- Estomatite aftosa ou úlceras aftosas orais
- Herpes simples
- Herpangina
Mais Diagnósticos diferenciaisDiretrizes
- Health protection in children and young people settings, including education
- Chinese guidelines for the diagnosis and treatment of hand, foot and mouth disease (2018 edition)
Mais Diretrizes
Conectar-se ou assinar para acessar todo o BMJ Best Practice
O uso deste conteúdo está sujeito ao nosso aviso legal