Summary
Definition
History and exam
Key diagnostic factors
- presença de fatores de risco
- desejo de movimentar as pernas
- disestesias
- sintomas no final do dia ou noturnos
- fatores de alívio (movimento, alongamento, massagem)
- localização nos membros inferiores, menos comumente nos membros superiores e tronco
Other diagnostic factors
- uso de bebidas alcoólicas
- consumo de cafeína
Risk factors
- afecções associadas à deficiência de ferro
- gestação
- história familiar de SPI
- uso de determinados medicamentos
- sexo feminino
- envelhecimento
- obesidade
- diabetes mellitus
- Doença de Parkinson
- esclerose múltipla
- neuropatia periférica
Diagnostic tests
1st tests to order
- diagnóstico clínico
- perfil de ferro
Treatment algorithm
SPI intermitente: não gestante
SPI intermitente: gestante
SPI persistente crônica: não gestante
SPI persistente crônica: gestante
SPI refratária: não gestante
SPI refratária: gestante
Contributors
Authors
Nitun Verma, MD, MBA
Sleep Physician
AC Wellness
Cupertino
CA
Disclosures
NV declares that he has no competing interests.
Clete A. Kushida, MD, PhD, RPSGT
Acting Medical Director
Stanford Sleep Medicine Center
Director
Stanford Center for Human Sleep Research
Associate Professor
Stanford University Medical Center
Stanford Sleep Medicine Center
Redwood City
CA
Disclosures
CAK is an author of a number of references cited in this topic.
Peer reviewers
Magdolna Hornyak, MD
Associate Professor
Interdisciplinary Pain Center and Department for Psychiatry and Psychotherapy
University Medical Center Freiburg
Freiburg
Germany
Раскрытие информации
MH declares that she has no competing interests.
K Ray Chaudhuri, MD, FRCP, DSc, FEAN
Professor of Movement Disorders and Neuroscience and Clinical Director
Parkinson Foundation International Centre of Excellence
King's College Hospital and King's College
Campus Research Director and Assistant Medical Director
King's College Hospital NHS Foundation Trust
London
UK
Раскрытие информации
KRC declares that he has no competing interests.
Brian Koo, MD
Associate Professor of Neurology
Yale University
New Haven
CT
Раскрытие информации
BK declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Список литературы
Основные статьи
Winkelman JW, Armstrong MJ, Allen RP, et al. Practice guideline summary: treatment of restless legs syndrome in adults - report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology. Neurology. 2016 Dec 13;87(24):2585-93.Полный текст Аннотация
American Academy of Sleep Medicine. The AASM international classification of sleep disorders - third edition, text revision (ICSD-3-TR). Jun 2023 [internet publication].Полный текст
Silber MH, Buchfuhrer MJ, Earley CJ, et al. The management of restless legs syndrome: an updated algorithm. Mayo Clin Proc. 2021 Jul;96(7):1921-37.Полный текст Аннотация
Winkelman JW, Berkowski JA, DelRosso LM, et al. Treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine clinical practice guideline. J Clin Sleep Med. 2025 Jan 1;21(1):137-52.Полный текст Аннотация
Allen RP, Picchietti DL, Auerbach M, et al. Evidence-based and consensus clinical practice guidelines for the iron treatment of restless legs syndrome/Willis-Ekbom disease in adults and children: an IRLSSG task force report. Sleep Med. 2018 Jan;41:27-44.Полный текст Аннотация
Статьи, указанные как источники
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Transtorno do movimento periódico dos membros (TMPM)
- Acatisia
- Neuropatia periférica
More DifferentialsGuidelines
- Treatment of restless legs syndrome and periodic limb movement disorder: an American Academy of Sleep Medicine clinical practice guideline
- International classification of sleep disorders, 3rd edition, text revision (ICSD-3-TR)
More Guidelines
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