小结
定义
病史和体格检查
关键诊断因素
- prurido
- pápulas ou placas violáceas, com a parte superior achatada
- estrias de Wickham
- erosões da mucosa e rede estriada e esbranquiçada
- alopecia cicatricial
- comprometimento ungueal
其他诊断因素
- pterígio dorsal
- história de hepatite C (HCV)
危险因素
- hepatite C (em algumas populações de pacientes)
- polimorfismo -308 G/A no gene fator de necrose tumoral (TNF)-alfa
- vacinação contra hepatite B
- vacinação contra gripe (influenza)
- vacinação contra a doença do coronavírus de 2019 (COVID-19)
- estresse psicossocial
- alérgenos orais
- uso de determinados medicamentos
诊断性检查
首要检查
- diagnóstico clínico
需考虑的检查
- histopatologia
- rastreamento de hepatite C (HCV)
- imunofluorescência
治疗流程
doença cutânea
doença do couro cabeludo
doença oral
doença genital
doença ungueal
撰稿人
作者
Deepani Munidasa, MBBS, MD
Consultant Dermatologist
Department of Dermatology
Anuradhapura Teaching Hospital
Anuradhapura
Sri Lanka
利益声明
DM declares that she has no competing interests.
鸣谢
Dr Deepani Munidasa would like to gratefully acknowledge Dr Susan Cooper, Dr Rebecca Dunn, Dr Julia S. Lehman, Dr Megha M. Tollefson, and Dr Lawrence E. Gibson, previous contributors to this topic.
利益声明
SC is chair of the British Society for the Study of Vulval Disease and receives royalties for contributions to UpToDate. RD, JSL, MMT, and LEG declare that they have no competing interests.
同行评议者
Brian Swick, MD
Clinical Assistant Professor
University of Iowa College of Medicine
Iowa City
IA
Declarações
BS declares that he has no competing interests.
David Cassarino, MD, PhD
Assistant Professor
Department of Pathology and Laboratory Medicine
University of California
Los Angeles
CA
Disclosures
DC declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
American College of Obstetricians and Gynecologists. Practice bulletin no. 224: diagnosis and management of vulvar skin disorders. Jul 2020 [internet publication].Full text Abstract
Edwards SK, Bates CM, Lewis F, et al. 2014 UK national guideline on the management of vulval conditions. Int J STD AIDS. 2015 Aug;26(9):611-24. Abstract
Ioannides D, Vakirlis E, Kemeny L, et al. European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology. J Eur Acad Dermatol Venereol. 2020 Jul;34(7):1403-14.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Líquen simples crônico
- Psoríase
- Líquen plano penfigoide
More DifferentialsGuidelines
- 2021 European guideline for the management of vulval conditions
- British Association of Dermatologists and British Photodermatology Group guidelines for narrowband ultraviolet B phototherapy
More Guidelines
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