Intoxicação por monóxido de carbono
Резюме
Определение
Анамнез и осмотр
Ключевые диагностические факторы
- presença de fatores de risco
- exposição ao fogo com inalação de fumaça
- náuseas
- cefaleia
- vômitos
- visão turva
- tontura
- vertigem
- alteração do nível de consciência
- dispneia
- taquicardia
- hipotensão ou hipertensão
- arritmia cardíaca
- dor
- fraqueza
- alterações no sono
- irritabilidade
- sintomas influenza-símiles
Другие диагностические факторы
- características neuropsiquiátricas tardias
- outros sintomas neurológicos graves
- bolhas cutâneas
- edema pulmonar
- exposição ao cloreto de metileno
- parada cardíaca
- anormalidades neurológicas focais (por exemplo, hemiplegia, ataxia troncular)
- coagulação intravascular disseminada
Факторы риска
- exposição à combustão incompleta de material contendo carbono
- exposição ao fogo com inalação de fumaça
- exposição ao cloreto de metileno
Диагностические исследования
Исследования, которые показаны в первую очередь
- nível de CO-Hb
- Eletrocardiograma (ECG)
- monitoramento cardíaco
- glicose sanguínea
- hemograma completo
- ureia e eletrólitos
- creatinina
- lactato
- nível de pH
- biomarcadores cardíacos
- creatina quinase
Исследования, проведение которых нужно рассмотреть
- radiografia torácica
- Miniexame do Estado Mental
- tomografia computadorizada (TC) do crânio
- imagem e espectroscopia por ressonância nuclear magnética
- testes da função hepática
- teste de gravidez
Алгоритм лечения
todos os pacientes
Составители
Авторы
Richard Moon, MD
Professor of Anesthesiology
Professor of Medicine
Division of Pulmonary, Allergy and Critical Care Medicine
Duke University
Durham
NC
Раскрытие информации
RM has been reimbursed by Merck for contributions to the Merck Manual.
Выражение благодарностей
Dr. Richard Moon would like to gratefully acknowledge Dr Jason Rose and Dr Prasanthi Govindarajan, previous contributors to this topic.
Раскрытие информации
PG declares that she has no competing interests. JR is a co-inventor on patent applications for the use of heme-based molecules as antidotes for CO poisoning. JR is a shareholder, officer, and director of Globin Solutions, Inc. Globin Solutions, Inc. has an exclusive license to this technology. Globin Solutions, Inc. had an option agreement to technology directed at using hydroxycobalamin for CO poisoning from Virginia Commonwealth University in the last 12 months. JR is an author of publications cited within this topic.
Рецензенты
Richard S. Weisman, PharmD
Director
Florida Poison Center
Miami
FL
Раскрытие информации
RSW declares that he has no competing interests.
Sean Patrick Nordt, MD, PharmD
Resident Physician
Department of Emergency Medicine
University of California
San Diego
CA
Divulgaciones
SPN declares that he has no competing interests.
Paul Hamilton, MD
Director
Department of Emergency Medicine
Mount Sinai School of Medicine
New York
NY
Divulgaciones
PH declares that he has no competing interests.
Ruben Thanacoody, MD, FRCP(Edin)
Consultant Physician and Clinical Toxicologist
Regional Drugs and Therapeutics Centre
Newcastle-upon-Tyne
UK
Divulgaciones
RT declares that he has no competing interests.
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Divulgaciones
Las afiliaciones y divulgaciones de los revisores por pares se refieren al momento de la revisión.
Referencias
Artículos principales
Hampson NB, Piantadosi CA, Thom SR, et al. Practice recommendations in the diagnosis, management, and prevention of carbon monoxide poisoning. Am J Respir Crit Care Med. 2012 Dec 1;186(11):1095-101.Texto completo Resumen
Centers for Disease Control and Prevention. Clinical guidance for carbon monoxide poisoning following disasters and severe weather. Jul 2024 [internet publication].Texto completo
Wolf SJ, Maloney GE, Shih RD, et al; American College of Emergency Physicians Clinical Policies Subcommittee (Writing Committee) on Carbon Monoxide Poisoning. Clinical policy: critical issues in the evaluation and management of adult patients presenting to the emergency department with acute carbon monoxide poisoning. Ann Emerg Med. 2017 Jan;69(1):98-107.e6.Texto completo Resumen
Weaver LK. Carbon monoxide poisoning (reprinted from the 2023 hyperbaric indications manual 15(th) edition). Undersea Hyperb Med. 2024 Third Quarter;51(3):253-76. Resumen
Artículos de referencia
Una lista completa de las fuentes a las que se hace referencia en este tema está disponible para los usuarios con acceso a todo BMJ Best Practice.
Diferenciales
- Infecção viral
- Intoxicação alcoólica
- Enxaqueca
Más DiferencialesGuías de práctica clínica
- Clinical policy: a critical issue in the management of adult patients presenting to the emergency department with acute carbon monoxide poisoning
- Clinical guidance for carbon monoxide poisoning following disasters and severe weather
Más Guías de práctica clínicaFolletos para el paciente
Intoxicação por monóxido de carbono
Más Folletos para el paciente
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