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Intoxicação por monóxido de carbono

最后审阅: 13 Feb 2025
最后更新: 21 Nov 2023

小结

定义

病史和体格检查

关键诊断因素

  • presença de fatores de risco
  • exposição ao fogo com inalação de fumaça
  • náuseas
  • cefaleia
  • vômitos
  • visão turva
  • tontura
  • vertigem
  • alteração do nível de consciência
  • dispneia
  • taquicardia
  • hipotensão ou hipertensão
  • arritmia cardíaca
  • dor
  • fraqueza
  • alterações no sono
  • irritabilidade
  • sintomas influenza-símiles
完整详情

其他诊断因素

  • características neuropsiquiátricas tardias
  • outros sintomas neurológicos graves
  • bolhas cutâneas
  • edema pulmonar
  • exposição ao cloreto de metileno
  • parada cardíaca
  • anormalidades neurológicas focais (por exemplo, hemiplegia, ataxia troncular)
  • coagulação intravascular disseminada
完整详情

危险因素

  • exposição à combustão incompleta de material contendo carbono
  • exposição ao fogo com inalação de fumaça
  • exposição ao cloreto de metileno
完整详情

诊断性检查

首要检查

  • nível de carboxi-hemoglobina
  • Eletrocardiograma (ECG)
  • monitoramento cardíaco
  • glicose sanguínea
  • hemograma completo
  • ureia e eletrólitos
  • creatinina
  • lactato
  • nível de pH
  • biomarcadores cardíacos
  • creatina quinase
完整详情

需考虑的检查

  • radiografia torácica
  • Miniexame do Estado Mental
  • tomografia computadorizada (TC) do crânio
  • imagem e espectroscopia por ressonância nuclear magnética
  • testes da função hepática
  • teste de gravidez
完整详情

治疗流程

急症处理

todos os pacientes

撰稿人

作者

Richard Moon, MD

Professor of Anesthesiology

Professor of Medicine

Division of Pulmonary, Allergy and Critical Care Medicine

Duke University

Durham

NC

利益声明

RM has been reimbursed by Merck for contributions to the Merck Manual.

鸣谢

Dr. Richard Moon would like to gratefully acknowledge Dr Jason Rose and Dr Prasanthi Govindarajan, previous contributors to this topic. PG declares that she has no competing interests. JR is a co-inventor on patent applications for the use of heme-based molecules as antidotes for CO poisoning. JR is a shareholder, officer, and director of Globin Solutions, Inc. Globin Solutions, Inc. has an exclusive license to this technology. Globin Solutions, Inc. had an option agreement to technology directed at using hydroxycobalamin for CO poisoning from Virginia Commonwealth University in the last 12 months. JR is an author of publications cited within this topic.

同行评议者

Richard S. Weisman, PharmD

Director

Florida Poison Center

Miami

FL

利益声明

RSW declares that he has no competing interests.

Sean Patrick Nordt, MD, PharmD

Resident Physician

Department of Emergency Medicine

University of California

San Diego

CA

利益声明

SPN declares that he has no competing interests.

Paul Hamilton, MD

Director

Department of Emergency Medicine

Mount Sinai School of Medicine

New York

NY

利益声明

PH declares that he has no competing interests.

Ruben Thanacoody, MD, FRCP(Edin)

Consultant Physician and Clinical Toxicologist

Regional Drugs and Therapeutics Centre

Newcastle-upon-Tyne

UK

利益声明

RT declares that he has no competing interests.

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