Resumo
Определение
Анамнез и осмотр
Ключевые диагностические факторы
- presença de fatores de risco
- linfadenopatia inguinal
- sintomas inespecíficos de proctocolite
- sinal de sulco de Greenblatt
- elefantíase genital, pênis saxofone, estiomene
Другие диагностические факторы
- febre, mal-estar, artralgias
- dor na parte inferior do abdome ou lombalgia
- úlcera genital ou anal
- sintomas inespecíficos de disseminação bacterêmica
- eritema nodoso
- tratos sinusais anogenitais, estenoses ou fístulas
Факторы риска
- outras ISTs
- comportamento sexual de risco
- soropositividade do vírus da imunodeficiência humana (HIV)
- idade (entre 20 e 40 anos)
- relação sexual sem proteção em uma área endêmica para LGV
- sexo masculino
Диагностические исследования
Исследования, которые показаны в первую очередь
- amostras genitais ou de linfonodos para o teste de amplificação de ácido nucleico (NAAT)
- swab via anoscopia para coloração de Gram
- fluido ou swab para testes moleculares específicos para LGV
- Testes para IST
Исследования, проведение которых нужно рассмотреть
- endoscopia com histopatologia
- soro para fixação de complemento
- soro para microimunofluorescência (MIF)
- tomografia computadorizada (TC) do abdome e pelve
- ressonância nuclear magnética (RNM) do abdome e pelve
- fluido ou swab para cultura
Неотложные исследования
- fluido ou swab para tipagem da variante genômica
Алгоритм лечения
adolescentes assintomáticos e pacientes adultos que tenham sido expostos a linfogranuloma venéreo (LGV)
todos os estágios do linfogranuloma venéreo (LGV)
Составители
Авторы
Benjamin D. Lorenz, MD
Assistant Professor
Division of Hospital Medicine
MedStar Georgetown University Hospital
Washington
DC
Раскрытие информации
BDL declares that he has no competing interests.
Выражение благодарностей
Dr Benjamin D. Lorenz would like to gratefully acknowledge Dr Mettassebia Kanno, a previous contributor to this topic.
Раскрытие информации
MK declares that she has no competing interests.
Рецензенты
Cees van Nieuwkoop, MD
Department of General Internal Medicine
Leiden University Medical Centre
Leiden
The Netherlands
Раскрытие информации
CvN declares that he has no competing interests.
David Chelmow, MD
Chair
Department of Obstetrics and Gynecology
Virginia Commonwealth University
Richmond
VA
Раскрытие информации
DC declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Список литературы
Основные статьи
de Vries HJC, de Barbeyrac B, de Vrieze NHN, et al. 2019 European guideline on the management of lymphogranuloma venereum. J Eur Acad Dermatol Venereol. 2019 Jun 26;33(10):1821-8.Полный текст Аннотация
Centers for Disease Control and Prevention. Lymphogranuloma venereum among men who have sex with men - Netherlands, 2003-2004. MMWR Morb Mortal Wkly Rep. 2004 Oct 29;53(42):985-8.Полный текст Аннотация
Van der Bij AK, Spaargaren J, Morre SA, et al. Diagnostic and clinical implications of anorectal lymphogranuloma venereum in men who have sex with men: a retrospective case-control study. Clin Infect Dis. 2006 Jan 15;42(2):186-94.Полный текст Аннотация
Stamm WE. Lymphogranuloma venereum. In: Holmes KK, Sparling PF, Stamm WE, et al., eds. Sexually transmitted diseases. 4th ed. New York, NY: McGraw Hill; 2007:595-606.
Workowski KA, Bachmann LH, Chan PA, et al. Sexually transmitted infections treatment guidelines, 2021. MMWR Recomm Rep. 2021 Jul 23;70(4):1-187.Полный текст Аннотация
Mabey D, Peeling RW. Lymphogranuloma venereum. Sex Transm Infect. 2002 Apr;78(2):90-2.Полный текст Аннотация
Thorsteinsson SB. Lymphogranuloma venereum: review of clinical manifestations, epidemiology, diagnosis, and treatment. Scand J Infect Dis Suppl. 1982;32:127-31. Аннотация
Annamuthodo H. Rectal lymphogranuloma venereum in Jamaica. Ann R Coll Surg Engl. 1961 Sep;29:141-59.Полный текст Аннотация
Статьи, указанные как источники
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Отличия
- Sífilis (Treponema pallidum)
- Proctite gonocócica
- Herpes genital (HSV)
Больше ОтличияРекомендации
- BASHH summary guidance on testing for sexually transmitted infections, 2023
- Sexually transmitted infections treatment guidelines, 2021
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