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Glaucoma de ângulo aberto

Last reviewed: 21 Jul 2025
Last updated: 12 Jun 2025

Summary

Definition

History and exam

Key diagnostic factors

  • presença de fatores de risco
  • razão escavação/disco >0.5
  • entalhe da escavação do nervo óptico
  • perda da visão periférica sintomática
  • aumento da pressão intraocular
  • escotomas
  • perda da camada de fibra nervosa
  • hemorragia do disco óptico
Full details

Other diagnostic factors

  • histerese da córnea
Full details

Risk factors

  • pressão intraocular >21 mmHg
  • idade >50 anos
  • histórico familiar de glaucoma
  • Anormalidades genéticas
  • etnia negra ou etnia hispânica
  • miopia
  • diabetes mellitus
  • hipertensão
  • baixa pressão de perfusão ocular
  • espessura fina da córnea central
  • histerese da córnea
  • bloqueadores dos canais de cálcio
Full details

Diagnostic investigations

1st investigations to order

  • tonometria
  • gonioscopia
  • oftalmoscopia direta
  • oftalmoscopia indireta
  • biomicroscopia com lâmpada de fenda
  • teste de campo visual
  • varredura por tomografia de coerência óptica
Full details

Investigations to consider

  • imagem digital
  • paquimetria
  • análise da camada de fibra nervosa
Full details

Emerging tests

  • histerese da córnea

Treatment algorithm

ACUTE

colírios preferenciais ou trabeculoplastia a laser contraindicados/falharam

preferência por trabeculoplastia a laser ou colírios contraindicados/falharam

colírios contraindicados/falharam e a doença é rapidamente progressiva

ONGOING

falha do tratamento

Contributors

Authors

Nishani Amerasinghe, MBBS, BSc(Hons), FRCOphth

Consultant Ophthalmic Surgeon

Glaucoma Specialist

University Hospital Southampton NHS Trust

Southampton

UK

Disclosures

NA is president-elect of the UK and Éire Glaucoma Society and has acted as an unpaid advisor to NICE and The Royal College of Ophthalmologists. NA has served on an advisory panel for Santen and has received travel honoraria and speaker's fees from Thea Pharmaceuticals, Santen, and Allergan. NA has received research funding from AbbVie Pharmaceuticals.

Irena Serov-Volach, MD

Senior Glaucoma and Cataract Fellow

Ophthalmology department

Eye Unit

Epsom and St Helier University Hospitals NHS Trust

London

UK

Disclosures

ISV has received consultancy/travel fees from Glaukos.

Acknowledgements

Dr Nishani Amerasinghe and Dr Irena Serov-Volach would like to gratefully acknowledge Dr Robert B. Avery and Dr Michael N. Wiggins, the previous contributors to this topic.

Disclosures

RBA and MNW declare that they have no competing interests.

Peer reviewers

Andrew Chen, MD

Assistant Professor

University of Washington

Seattle

WA

Disclosures

AC declares that he has received research funding from Janssen LLC.

Sheila Sanders, MD

​Professor of Ophthalmology

University of Kentucky

South Limestone

Lexington

KY

Disclosures

SS declares that she has no competing interests.

Mohamed Khodeiry, MD

Glaucoma Fellow

University of Kentucky

South Limestone

Lexington

KY

Disclosures

MK declares that he has no competing interests.

Roshini Sanders, FRCS, FRCOphth

Consultant Ophthalmologist

Queen Margaret Hospital

Dunfermline

Fife

UK

Disclosures

RS declares that she has no competing interests.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Weinreb RN, Leung CK, Crowston JG, et al. Primary open-angle glaucoma. Nat Rev Dis Primers. 2016 Sep 22;2:16067. Abstract

International Council of Ophthalmology. ICO guidelines for glaucoma eye care. Feb 2016 [internet publication].Full text

American Academy of Ophthalmology. Primary open-angle glaucoma preferred practice pattern. Nov 2020 [internet publication].Full text

American Academy of Ophthalmology. Primary open-angle glaucoma suspect preferred practice pattern. Nov 2020 [internet publication].Full text

National Institute for Health and Care Excellence. Glaucoma: diagnosis and management. Jan 2022 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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