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Depósito de pirofosfato de cálcio

Last reviewed: 18 Aug 2025
Last updated: 15 Feb 2024

Summary

Definition

Анамнез и осмотр

Ключевые диагностические факторы

  • presença de fatores de risco
  • articulações doloridas e sensíveis
  • comprometimento de articulações semelhantes a osteoartrite (punhos, ombros)
  • piora súbita da osteoartrite
Полная информация

Другие диагностические факторы

  • articulações avermelhadas e edemaciadas
  • derrame articular e flutuação
  • febre e mal-estar
Полная информация

Факторы риска

  • idade avançada
  • lesão
  • hiperparatireoidismo
  • hemocromatose
  • história familiar de DPFC
  • hipomagnesemia
  • hipofosfatasia
  • gota
  • outras condições metabólicas
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • artrocentese com análise do líquido sinovial
  • radiografias das articulações afetadas
  • cálcio sérico
  • paratormônio sérico
  • perfil de ferro
  • magnésio sérico
  • fosfatase alcalina sérica
Полная информация

Исследования, проведение которых нужно рассмотреть

  • ultrassonografia
  • Tomografia computadorizada (TC)
Полная информация

Алгоритм лечения

Острый

doença monoarticular ou oligoarticular

doença poliarticular

ПРОДОЛЖЕНИЕ

comprometimento crônico e recorrente da articulação do joelho, quadril ou ombro com degeneração grave

com doença do tipo osteoartrite ou do tipo reumatoide

Составители

Авторы

Ann K. Rosenthal, MD
Ann K. Rosenthal

Professor of Medicine

Medical College of Wisconsin

Milwaukee

WI

Раскрытие информации

AKR is the author of several articles cited in this topic.

Рецензенты

Priyanka Iyer, MD

Clinical Assistant Professor

University of California, Irvine

Irvine

CA

Раскрытие информации

PI declares that she has no competing interests.

Ade Adebajo, MBBS, MSc, FRCP (Glasgow), FACP

Consultant Rheumatologist

Rheumatology

University of Sheffield Medical School

Sheffield

UK

Раскрытие информации

AA declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

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Основные статьи

McCarty DJ. Diagnostic mimicry in arthritis: patterns of joint involvement associated with calcium pyrophosphate dihydrate crystal deposits. Bull Rheum Dis. 1975;25:804-809.

Zhang W, Doherty M, Bardin T, et al. European League Against Rheumatism recommendations for calcium pyrophosphate deposition. Part I: terminology and diagnosis. Ann Rheum Dis. 2011 Apr;70(4):563-70.Полный текст  Аннотация

Rosenthal AK, Ryan LM. Calcium Pyrophosphate Deposition Disease. N Engl J Med. 2016 Jun 30;374(26):2575-84.Полный текст  Аннотация

Martinez Sanchis A, Pascual E. Intracellular and extracellular CPPD crystals are a regular feature in synovial fluid from uninflamed joints of patients with CPPD related arthropathy. Ann Rheum Dis. 2005 Dec;64(12):1769-72. Аннотация

Zhang W, Doherty M, Pascual E, et al. EULAR recommendations for calcium pyrophosphate deposition. Part II: management. Ann Rheum Dis. 2011 Apr;70(4):571-5.Полный текст  Аннотация

Creamer P. Intra-articular corticosteroid treatment in osteoarthritis. Curr Opin Rheumatol. 1999 Sep;11(5):417-21. Аннотация

Статьи, указанные как источники

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