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Prolactinoma

Última revisão: 17 Aug 2025
Última atualização: 22 Jul 2022

Resumo

Definição

ანამნეზი და გასინჯვა

ძირითადი დიაგნოსტიკური ფაქტორები

  • presença de fatores de risco
  • amenorreia ou oligomenorreia
  • infertilidade
  • galactorreia
  • perda do desejo sexual (libido)
  • disfunção erétil
  • deterioração visual (por exemplo, hemianopsia temporal)
სრული ტექსტი

სხვა დიაგნოსტიკური ფაქტორები

  • osteoporose
  • oftalmoplegia
  • cefaleias
სრული ტექსტი

რისკფაქტორები

  • predisposição genética (por exemplo, presença de mutação resultando em neoplasia endócrina múltipla-1 [NEM-1], adenoma hipofisário familiar isolado [FIPA])
  • terapia estrogênica
  • sexo masculino, de 30 a 60 anos de idade
  • sexo feminino, de 20 a 50 anos de idade
სრული ტექსტი

დიაგნოსტიკური კვლევები

1-ად შესაკვეთი გამოკვლევები

  • prolactina sérica
  • ressonância nuclear magnética (RNM) da hipófise
  • exame do campo visual computadorizado
სრული ტექსტი

მკურნალობის ალგორითმი

持续性治疗

mulheres na pré-menopausa

mulheres menopausadas

homens

撰稿人

作者

Niamh Martin, MB ChB, PhD, FRCP

Reader in Endocrinology

Imperial Centre for Endocrinology

Department of Metabolism, Digestion and Reproduction

Imperial College London

London

UK

利益声明

NM declares that she has no competing interests.

鸣谢

Dr Niamh Martin would like to gratefully acknowledge Dr Ilan Shimon, the previous contributor to this topic.

利益声明

IS receives consultancy and lecturing fees from Pfizer, Israel, and is an author of a number of references cited in this topic.

同行评议者

Mark Molitch, MD

Professor

Division of Endocrinology

Northwestern University Feinberg School of Medicine

Chicago

IL

利益声明

MM is an author of a number of references cited in this topic.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

Wildemberg LE, Fialho C, Gadelha MR. Prolactinomas. Presse Med. 2021 Dec;50(4):104080.全文  摘要

Melmed S, Casanueva FF, Hoffman AR, et al; Endocrine Society. Diagnosis and treatment of hyperprolactinemia: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011 Feb;96(2):273-88.全文  摘要

Xia MY, Lou XH, Lin SJ, et al. Optimal timing of dopamine agonist withdrawal in patients with hyperprolactinemia: a systematic review and meta-analysis. Endocrine. 2018 Jan;59(1):50-61. 摘要

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
  • Prolactinoma images
  • 鉴别诊断

    • Macroadenomas hipofisários não funcionantes
    • Hiperprolactinemia induzida por medicamentos
    • Hipotireoidismo primário
    更多 鉴别诊断
  • 指南

    • Position statement for clinical practice: prolactin-secreting tumors
    • ACR appropriateness criteria: neuroendocrine imaging
    更多 指南
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