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Transtorno obsessivo-compulsivo

Last reviewed: 4 May 2025
Last updated: 23 Aug 2024

Summary

Definition

History and exam

Key diagnostic factors

  • presença de fatores de risco
  • obsessões
  • compulsões
  • fenômenos sensoriais
  • transtorno de personalidade esquizotípica
  • transtorno de tique
  • coordenação motora reduzida
  • dificuldades sensório-perceptivas
  • dificuldades no sequenciamento de tarefas motoras complexas
Full details

Other diagnostic factors

  • sexo masculino
Full details

Risk factors

  • história familiar de TOC
  • PANDAS (transtornos neuropsiquiátricos autoimunes pediátricos associados à infecção por estreptococos)
  • gestação
  • sexo masculino (início mais cedo, evolução mais crônica e resistência ao tratamento)
  • maior frequência das compulsões (resistência ao tratamento)
  • idade precoce de início (resistência ao tratamento)
  • hospitalizações anteriores devidas ao TOC (resistência ao tratamento)
  • transtorno de personalidade esquizotípica (resistência ao tratamento)
  • transtorno de tique (resistência ao tratamento)
  • anormalidades estruturais do cérebro específicas ou difusas (resistência ao tratamento)
Full details

Diagnostic investigations

1st investigations to order

  • nenhum exame inicial
Full details

Investigations to consider

  • Entrevista Clínica Estruturada do DSM (SCID)
  • Escala de Sintomas Obsessivo-Compulsivos de Yale-Brown (Y-BOCS)
  • Impressão clínica global (CGI)
Full details

Treatment algorithm

ACUTE

sintomas leves a moderados: sem transtornos de personalidade comórbidos ou sintomas dissociativos

sintomas graves ou com transtornos de personalidade comórbidos ou sintomas dissociativos

Contributors

Authors

Phillip J. Seibell, MD, FAPA
Phillip J. Seibell

OCD and Anxiety Psychiatry of Westchester, P.C.

Hawthorne

NY

Disclosures

PJS has received honoraria from Slack, Inc., for guest editing an issue on OCD.

Stefano Pallanti, MD, PhD
Stefano Pallanti

Professor of Psychiatry

Institute of Neuroscience

Florence

Italy

Disclosures

SP declares that he has no competing interests. SP is an author of several references cited in this topic.

Silvia Bernardi, MD
Silvia Bernardi

Project Manager

New York State Psychiatric Institute

Columbia University

New York

NY

Disclosures

SB receives research sponsorship from NYSPI, APA, and the Brain & Behavior Research Foundation. SB is also a board member of the New York council on Problem Gambling. SB is an author of a reference cited in this topic.

Megan Hughes-Feltenberger, PhD
Megan Hughes-Feltenberger

Assistant Professor of Psychology in Psychiatry

Assistant Director of Education for Psychology

Weill Cornell Medical College

Assistant Attending Psychologist

NewYork-Presbyterian Hospital

New York

NY

Disclosures

MHF declares that she has no competing interests.

Eric Hollander, MD
Eric Hollander

Clinical Professor of Psychiatry and Behavioral Sciences

Director

Compulsive, Impulsive and Autism Spectrum Disorder Program

Albert Einstein College of Medicine

Montefiore Medical Center

New York

NY

Disclosures

EH has received research grants from, and has consulted for, Roche, GW Pharmaceuticals, and Bixink.

Acknowledgements

The authors would like to gratefully acknowledge Dr Ashley Braun, a previous contributor to this topic. AB declares that she has no competing interests.

Peer reviewers

Juliana Belo Diniz, MD

Psychiatrist

Department and Institute of Psychiatry

Clinical Hospital

University of Sao Paulo Medical School

Sao Paulo

Brazil

Disclosures

JBD declares that she has no competing interests.

Amit Nigam, MBBS, MRCPsych

Specialist Registrar in Forensic Psychiatry and Honorary Research Worker

National OCD Service

Queen Elizabeth II Hospital

Welwyn Garden City

Forensic Psychiatrist

West London Mental Health NHS Trust

London

UK

Disclosures

AN declares that he has no competing interests.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 5th edition, text revision (DSM-5-TR). Washington, DC: American Psychiatric Publishing; 2022.

World Health Organization. International statistical classification of diseases and related health problems. 11th revision. Jan 2022 [internet publication].Full text

American Psychiatric Association. Practice guideline for the treatment of patients with obsessive-compulsive disorder. Am J Psychiatry. July 2007 [internet publication].Full text

American Psychiatric Association. Guideline watch (March 2013): Practice guideline for the treatment of patients with obsessive-compulsive disorder. March 2013 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
  • Differentials

    • Transtorno de personalidade obsessivo-compulsivo (TPOC)
    • Transtorno dismórfico corporal (TDC)
    • Transtorno de sintomas somáticos
    More Differentials
  • Guidelines

    • Diagnostic and statistical manual of mental disorders, fifth edition, text revision (DSM-5-TR)
    • Deep brain stimulation for obsessive-compulsive disorder
    More Guidelines
  • Patient information

    Transtorno obsessivo-compulsivo

    More Patient information
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