Резюме
定义
病史和体格检查
关键诊断因素
- presença de fatores de risco
- taquicardia
- hipertensão
- hipertermia
- agitação
- midríase
- diaforese
其他诊断因素
- convulsões
危险因素
- temperatura ambiente elevada
- pobreza
- body packing de cocaína
- sexo masculino
- deficiência de colinesterase plasmática
- idade entre 18-25 anos
- história de uso de cocaína
- uso concomitante de outros simpatomiméticos
诊断性检查
首要检查
- eletrocardiograma (ECG)
- glicose sérica à beira do leito
- creatinina sérica
- ureia
- creatina fosfoquinase sérica (CPK)
- troponina sérica
- radiografia torácica
- tomografia computadorizada (TC) cranioencefálica
需考虑的检查
- teste de cocaína na urina
- tomografia computadorizada (TC) de abdome e pelve
治疗流程
toxicidade por cocaína suspeitada/confirmada: exceto "mula" de tráfico/body stuffer
toxicidade por cocaína suspeitada/confirmada: "mula" de tráfico/body stuffer
撰稿人
作者
Andrew Stolbach, MD, MPH
Attending Physician
Johns Hopkins Hospital
Baltimore
MD
利益声明
AS has been reimbursed by Peerview Education for delivering educational lectures unrelated to this topic; for expert testimony in unrelated toxicology topics; and by UpToDate for writing articles on other toxicology topics.
同行评议者
Janice Zimmerman, MD
Head
Critical Care Division
The Methodist Hospital
Houston
TX
利益声明
JZ declares that she has no competing interests. JZ is the author of an article cited in this text, but the article was not included in the text at the time of her peer review.
Alison Jones, MD, FRCPE, FiBIOL, FRCP, FRACP
Dean
School of Medicine
Campbelltown Campus
University of Western Sydney
Australia
利益声明
AJ declares that she has no competing interests.
Andrew Parfitt, MBBS, FFAEM
Clinical Director
Acute Medicine
Associate Medical Director
Consultant Emergency Medicine
Guy's and St Thomas' NHS Foundation Trust
Clinical Lead and Consultant
Accident Emergency Medicine
St Thomas' Hospital
London
UK
利益声明
AP declares that he has no competing interests.
参考文献
关键文献
Lavonas EJ, Akpunonu PD, Arens AM, et al. 2023 American Heart Association focused update on the management of patients with cardiac arrest or life-threatening toxicity due to poisoning: an update to the American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2023 Oct 17;148(16):e149-84.全文 摘要
Royal College of Emergency Medicine. Management of suspected internal drug trafficker (SIDT). Dec 2020 [internet publication].全文
Panchal AR, Bartos JA, Cabañas JG, et al. Part 3: adult basic and advanced life support: 2020 American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care. Circulation. 2020 Oct 20;142(16_suppl_2):S366-468.全文
Smollin CG, Hoffman RS. Chapter 75: Cocaine. In: Nelson LS, Howland MA, Lewin NA, et al, eds. Goldfrank's toxicologic emergencies, 11th ed. New York, NY: McGraw-Hill Education; 2019.
参考文献
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
鉴别诊断
- Overdose de simpatomiméticos diferentes da cocaína
- Abstinência alcoólica, de sedativos ou de hipnóticos
- Síndrome anticolinérgica
更多 鉴别诊断指南
- Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders
- 2023 American Heart Association focused update on the management of patients with cardiac arrest or life-threatening toxicity due to poisoning: an update to the American Heart Association guidelines for cardiopulmonary resuscitation and emergency cardiovascular care
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