Резюме
Определение
Анамнез и осмотр
Ключевые диагностические факторы
- presença de fatores de risco
- flutuações
- alucinações visuais
- Sintomas motores
- distúrbio comportamental do sono de movimento rápido dos olhos (REM)
Другие диагностические факторы
- grave sensibilidade ao antipsicótico
- depressão
- ansiedade
- quedas repetidas e síncope
- hipotensão ortostática
- sintomas urinários
- constipação
- anormalidades da atenção e do processamento visual
- delírios
- Hipersonia
- hiposmia
- alucinações auditivas
Факторы риска
- idade avançada
- ocorrência familiar
Диагностические исследования
Исследования, которые показаны в первую очередь
- hormônio estimulante da tireoide (TSH) sérico
- vitamina B12 sérica
- tomografia computadorizada (TC) do crânio
- ressonância nuclear magnética (RNM) de crânio
Исследования, проведение которых нужно рассмотреть
- Hemograma completo
- perfil metabólico
- folato sérico
- teste sérico do VDRL (Venereal Disease Research Laboratory, laboratório de pesquisa de doenças venéreas)
- exame de urina para detecção de drogas
- urinálise
- teste de vírus da imunodeficiência humana (HIV)
- TC por emissão de fóton único (SPECT)/tomografia por emissão de pósitrons (PET)
- EEG quantitativo
- polissonografia
- Análise do líquido cefalorraquidiano (LCR)
- exame neuropsicológico
- cintilografia miocárdica com metaiodobenzilguanidina (MIBG)
Алгоритм лечения
todos os pacientes
Составители
Авторы
Alan J. Lerner, MD
Professor of Neurology
Department of Neurology
University Hospitals Cleveland Medical Center
Case Western Reserve University
Cleveland
OH
Раскрытие информации
AJL declares that he has no competing interests.
Mohamed I. Elkasaby, MD
Fellow in Behavioral Neurology and Neuropsychiatry
Department of Neurology
University Hospitals Cleveland Medical Center
Case Western Reserve University
Cleveland
OH
Раскрытие информации
MIE declares that he has no competing interests.
Выражение благодарностей
Dr Alan J. Lerner and Dr Mohamed I. Elkasaby would like to gratefully acknowledge Dr Brian S. Appleby, Dr Ethan Gore, Dr Rajeet Shrestha, Dr Timothy Wuerz, Dr Julie Schneider, Dr Viola Fahmy, and Dr Sube Banerjee, previous contributors to this topic.
Раскрытие информации
BSA, EG, RS, TW, JS, VF, and SB declare that they have no competing interests.
Рецензенты
Bryan Bernard, PhD
Assistant Professor and Clinical Neuropsychologist
Department of Neurological Sciences
Rush University Medical Center
Chicago
IL
Раскрытие информации
BB declares that he has no competing interests.
James E. Galvin, MD, MPH
Associate Professor
Neurology, Psychiatry and Neurobiology
Director
Memory Diagnostic Center and Alzheimer Treatment Unit
Director
Education and Community Outreach
Alzheimer Disease Research Center
Washington University School of Medicine
St Louis
MO
Раскрытие информации
JEG declares that he has no competing interests.
Ian McKeith, MBBS
Professor of Old Age Psychiatry
Clinical Director
Institute for Ageing and Health
Newcastle University
Newcastle
UK
Раскрытие информации
IM is the author of several references cited in this topic.
Список литературы
Основные статьи
McKeith IG, Boeve BF, Dickson DW, et al. Diagnosis and management of dementia with Lewy bodies: fourth consensus report of the DLB Consortium. Neurology. 2017 Jul 4;89(1):88-100.Полный текст Аннотация
Expert Panel on Neurological Imaging; Moonis G, Subramaniam RM, Trofimova A, et al. ACR Appropriateness Criteria® dementia. J Am Coll Radiol. 2020 May;17(5s):S100-12.Полный текст Аннотация
Taylor JP, McKeith IG, Burn DJ, et al. New evidence on the management of Lewy body dementia. Lancet Neurol. 2020 Feb;19(2):157-69.Полный текст Аннотация
O'Brien JT, Holmes C, Jones M, et al. Clinical practice with anti-dementia drugs: a revised (third) consensus statement from the British Association for Psychopharmacology. J Psychopharmacol. 2017 Feb;31(2):147-68. Аннотация
Rolinski M, Fox C, Maidment I, et al. Cholinesterase inhibitors for dementia with Lewy bodies, Parkinson's disease dementia and cognitive impairment in Parkinson's disease. Cochrane Database Syst Rev. 2012 Mar 14;(3):CD006504.Полный текст Аннотация
Reus VI, Fochtmann LJ, Eyler AE, et al. The American Psychiatric Association practice guideline on the use of antipsychotics to treat agitation or psychosis in patients with dementia. Am J Psychiatry. 2016 May 1;173(5):543-6.Полный текст Аннотация
Статьи, указанные как источники
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
鉴别诊断
- Doença de Alzheimer
- Doença de Parkinson
- Demência frontotemporal
更多 鉴别诊断指南
- Management of REM sleep behavior disorder
- ACR appropriateness criteria: dementia
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