Úlcera péptica

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Evidence last reviewed: 21 Aug 2026
Topic last updated: 30 Jul 2025

Summary

Definition

History and exam

Key diagnostic factors

  • dor abdominal
  • presença de fatores de risco
  • "sinal de apontar"
Full details

Other diagnostic factors

  • desconforto epigástrico
  • náuseas ou vômitos
  • saciedade precoce
  • perda de peso ou anorexia
  • diarreia
  • sintomas de anemia
  • hemorragia digestiva
  • hipotensão ou choque séptico
  • som de sucussão
Full details

Risk factors

  • infecção por Helicobacter pylori
  • uso de anti-inflamatórios não esteroidais (AINEs)
  • tabagismo
  • idade mais avançada
  • história pessoal de úlcera péptica
  • história familiar de úlcera péptica
  • paciente de terapia intensiva
  • trabalho por turnos
Full details

Diagnostic tests

1st tests to order

  • endoscopia digestiva alta
  • Teste respiratório de ureia com carbono 13 para Helicobacter pylori ou teste de antígeno fecal
  • Hemograma completo
Full details

Tests to consider

  • nível de gastrina sérica em jejum
  • exame de AINE na urina
Full details

Treatment algorithm

ACUTE

úlcera com sangramento ativo

sem sangramento ativo: Helicobacter pylori negativo

sem sangramento ativo: Helicobacter pylori positivo

ONGOING

úlceras recorrentes ou refratárias

Contributors

Expert advisers

Ian Beales, BSc, MD, FRCP, FEBG

Consultant Gastroenterologist

Clinical Associate Professor

Norwich Medical School

Department of Gastroenterology

Norfolk and Norwich University Hospital

Norwich

UK

Disclosures

IB declares that he has no competing interests.

Acknowledgements

BMJ Best Practice would like to gratefully acknowledge the previous expert contributor, whose work has been retained in parts of the content:

Kristle Lee Lynch, MD

Assistant Professor of Clinical Medicine

Division of Gastroenterology

Department of Medicine

Hospital of the University of Pennsylvania

University of Pennsylvania

Perelman School of Medicine

Philadelphia

PA

Раскрытие информации

​​​​​KLL ​​​​declares that she has no competing interests.

Рецензенты

Alexander C Ford, MBChB, MD, FRCP

Professor of Gastroenterology

Honorary Consultant Gastroenterologist

Leeds Institute of Medical Research at St. James's

University of Leeds

Leeds Gastroenterology Institute

Leeds Teaching Hospitals Trust

Leeds

UK

Биография

ACF served on the National Institute for Health and Care Excellence (NICE) guideline committee for clinical guideline CG184: Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management.

Раскрытие информации

ACF declares that he has no competing interests. ACF is an author of a Cochrane systematic review cited in this topic.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

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Основные статьи

National Institute for Health and Care Excellence. Gastro-oesophageal reflux disease and dyspepsia in adults: investigation and management. Oct 2019 [internet publication].Полный текст

UK Health Security Agency. Helicobacter pylori in dyspepsia: test and treat. Jan 2025 [internet publication].Полный текст

Moayyedi PM, Lacy BE, Andrews CN, et al. ACG and CAG clinical guideline: management of dyspepsia. Am J Gastroenterol. 2017 Jul;112(7):988-1013.Полный текст  Аннотация

National Institute for Health and Care Excellence. Acute upper gastrointestinal bleeding in over 16s: management. August 2016 [internet publication].Полный текст

Siau K, Hearnshaw S, Stanley AJ, et al. British Society of Gastroenterology (BSG)-led multisociety consensus care bundle for the early clinical management of acute upper gastrointestinal bleeding. Frontline Gastroenterol. 2020;11(4):311-23.Полный текст  Аннотация

Статьи, указанные как источники

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