Резюме
Определение
Анамнез и осмотр
Ключевые диагностические факторы
- presença de fatores de risco
- idade entre 20 e 34 anos
- massa testicular
Другие диагностические факторы
- manifestação extratesticular
Факторы риска
- criptorquidia
- disgenesia gonadal
- história familiar de câncer de testículo
- história pessoal de câncer de testículo
- atrofia testicular
- etnia branca
- Infecção pelo vírus da imunodeficiência humana (HIV)
- exposições ocupacionais
- hérnia inguinal
- anormalidade genética
Диагностические исследования
Исследования, которые показаны в первую очередь
- ultrassonografia com Doppler colorido do testículo
- exame de imagem torácica
- Tomografia computadorizada de abdome e pelve com contraste
- gonadotrofina coriônica humana beta sérica (beta-hCG)
- alfafetoproteína sérica (AFP)
- lactato desidrogenase (LDH) sérica
- exame histológico da massa testicular pós-orquiectomia
Исследования, проведение которых нужно рассмотреть
- fosfatase alcalina placentária sérica
- ressonância nuclear magnética (RNM) abdominal e pélvica
- TC do tórax
- biópsia do testículo contralateral
Treatment algorithm
massa testicular suspeita
seminoma em estádio inicial
não seminoma em estádio inicial
seminoma ou não seminoma: doença em estádio IIC ou estádio III
seminoma ou não seminoma: doença recidivante
Contributors
Authors
Al B. Barqawi, MD, FRCS
Professor of Surgery/Urology
University of Colorado Anschutz Medical Campus
Aurora
CO
Disclosures
ABB declares that he has no competing interests.
Corbin J. Eule, MD
Assistant Professor of Medical Oncology
University of Colorado Anschutz Medical Campus
Aurora
CO
Disclosures
CJE declares that he has no competing interests.
Acknowledgements
Dr Al B. Barqawi and Dr Corbin J. Eule would like to gratefully acknowledge Dr Elizabeth R. Kessler, Dr Thomas W. Flaig, and Dr Brandon Bernard, previous contributors to this topic.
Disclosures
ERK, TWF, and BB declare that they have no competing interests.
Peer reviewers
Elisabeth Heath, MD
Assistant Professor of Medicine and Oncology
Karmanos Cancer Institute
Wayne State University
Detroit
MI
Disclosures
EH declares that she has no competing interests.
Gianfilippo Bertelli, MD, PhD, FRCP (Edin)
Consultant/Honorary Senior Lecturer in Medical Oncology
SW Wales Cancer Institute/Department of Oncology
Singleton Hospital
Sketty
Swansea
UK
Disclosures
GB declares that he has no competing interests.
Emilio Porfiri, MD, PhD
Senior Lecturer in Medical Oncology
School of Cancer Sciences
University of Birmingham
Birmingham
UK
Disclosures
EP declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
Stephenson A, Bass EB, Bixler BR, et al. Diagnosis and treatment of early-stage testicular cancer: AUA guideline amendment 2023. J Urol. 2024 Jan;211(1):20-5.Full text Abstract
European Association of Urology. Testicular cancer. 2024 [internet publication].Full text
Oldenburg J, Berney DM, Bokemeyer C, et al. Testicular seminoma and non-seminoma: ESMO-EURACAN clinical practice guideline for diagnosis, treatment and follow-up. Ann Oncol. 2022 Apr;33(4):362-75.Full text Abstract
National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: testicular cancer [internet publication].Full text
American College of Radiology. ACR appropriateness criteria: staging and surveillance of testicular cancer. 2021 [internet publication].Full text
Gillessen S, Sauvé N, Collette L, et al. Predicting outcomes in men with metastatic nonseminomatous germ cell tumors (NSGCT): results from the IGCCCG update consortium. J Clin Oncol. 2021 May 10;39(14):1563-74.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Torção testicular
- Epidídimo-orquite
- Hérnia escrotal
More DifferentialsGuidelines
- NCCN clinical practice guidelines in oncology: testicular cancer
- Diagnosis and treatment of early stage testicular cancer
More GuidelinesPatient information
Câncer de testículo
Câncer de testículo: perguntas a fazer ao seu médico
More Patient information
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