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Angina instável

Last reviewed: 13 Jul 2025
Last updated: 11 Mar 2025

Summary

Definition

History and exam

Key diagnostic factors

  • presença de fatores de risco
  • Dor torácica
Full details

Other diagnostic factors

  • diaforese
  • dor epigástrica
  • dispneia
  • náuseas e vômitos
  • sopro carotídeo
  • pulsos periféricos reduzidos ou ausentes
  • síncope
  • dorsalgia
  • arritmias
  • bulhas cardíacas anormais
  • estertores
Full details

Risk factors

  • tabagismo
  • hipertensão
  • diabetes mellitus
  • obesidade e síndrome metabólica
  • comportamento sedentário e inatividade física
  • dislipidemia
  • doença renal crônica (DRC)
  • aterosclerose (história de angina, IAM, AVC, ataque isquêmico transitório, doença vascular periférica)
  • história familiar de DAC prematura
  • idade >60 anos
  • uso de cocaína
  • depressão
  • apneia do sono
  • Níveis elevados de proteína C-reativa
  • radiação do mediastino
  • enxaqueca
  • desfechos adversos da gestação
Full details

Diagnostic tests

1st tests to order

  • eletrocardiograma (ECG)
  • biomarcadores cardíacos
  • radiografia torácica
  • Hemograma completo
  • eletrólitos e função renal
  • TFHs
  • glicemia
  • proteína C-reativa
  • perfil lipídico
  • perfil de coagulação
Full details

Tests to consider

  • ecocardiograma
  • angiografia coronariana
  • teste funcional (de estresse)
  • angiotomografia coronária
  • tomografia computadorizada (TC) do tórax ou ressonância nuclear magnética (RNM)
Full details

Treatment algorithm

INITIAL

dor torácica presumivelmente cardíaca

ACUTE

síndrome coronariana aguda sem supradesnivelamento do segmento ST

ONGOING

pós-estabilização: angina instável (AI) confirmada (biomarcadores cardíacos não elevados)

Contributors

Authors

Syed Wamique Yusuf, MBBS, FRCPI
Syed Wamique Yusuf

Professor of Medicine

Department of Cardiology

University of Texas

MD Anderson Cancer Center

Houston

TX

Disclosures

SWY declares that he has no competing interests.

Acknowledgements

Dr Syed Wamique Yusuf would like to gratefully acknowledge Dr Iyad N. Daher, the previous contributor to this topic.

Disclosures

IND declares that he has no competing interests.

Peer reviewers

John Charpie, MD, PhD

Associate Professor of Pediatrics

Medical Director

Pediatric Cardiothoracic Intensive Care Unit

University of Michigan Congenital Heart Center

Ann Arbor

MI

Disclosures

JC declares that he has no competing interests.

Zaza Iakobishvili, MD, PhD

Director

Emergency Cardiac Service ICCU

Department of Cardiology

Rabin Medical Center

Petah Tikva

Israel

Disclosures

ZI declares that he has no competing interests.

Helge Mollmann, MD

Kerckhoff Heart and Thorax Center

Bad Nauheim

Germany

Disclosures

HM declares that he has no competing interests.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Byrne RA, Rossello X, Coughlan JJ, et al. 2023 ESC guidelines for the management of acute coronary syndromes. Eur Heart J. 2023 Oct 12;44(38):3720-826.Full text  Abstract

Amsterdam EA, Wenger NK, Brindis RG, et al. 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014 Dec 23;64(24):e139-228.Full text  Abstract

Gulati M, Levy PD, Mukherjee D, et al. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR guideline for the evaluation and diagnosis of chest pain: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2021 Nov 30;78(22):e187-285.Full text  Abstract

Lawton JS, Tamis-Holland JE, Bangalore S, et al. 2021 ACC/AHA/SCAI guideline for coronary artery revascularization: a report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2022 Jan 18;145(3):e18-114.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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