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Síndrome do ovário policístico

Last reviewed: 14 Sep 2025
Last updated: 09 Feb 2024

Summary

Definition

History and exam

Key diagnostic factors

  • presença de fatores de risco
  • mulheres em idade fértil
  • menstruação irregular
  • infertilidade
  • hirsutismo
Full details

Other diagnostic factors

  • acne
  • sobrepeso ou obesidade
  • hipertensão
  • queda de cabelos
  • pele oleosa ou sudorese excessiva
  • acantose nigricans
Full details

Risk factors

  • história familiar de síndrome do ovário policístico (SOPC)
  • adrenarca prematura
  • obesidade
  • baixo peso ao nascer
  • exposição do feto ao androgênio
  • interferências endócrinas causadas pelo ambiente
Full details

Diagnostic investigations

1st investigations to order

  • 17-hidroxiprogesterona sérica
  • prolactina sérica
  • hormônio estimulante da tireoide sérico
  • teste oral de tolerância à glicose
  • perfil lipídico em jejum
Full details

Investigations to consider

  • testosterona sérica total e livre
  • sulfato de desidroepiandrosterona sérico (DHEA-S)
  • androstenediona sérica
  • ultrassonografia pélvica
  • hormônio antimülleriano sérico
  • monitoramento da temperatura basal do corpo
  • medição do progesterona na fase lútea
  • LH e hormônio folículo-estimulante (FSH) séricos
  • hemoglobina A1c ou glicemia de jejum
Full details

Treatment algorithm

ACUTE

com infertilidade e fertilidade desejada

ONGOING

não desejam a fertilidade atualmente

Contributors

Authors

Mark O. Goodarzi, MD, PhD
Mark O. Goodarzi

Division of Endocrinology, Diabetes & Metabolism

Eris M. Field Chair in Diabetes Research

Professor of Medicine

Cedars-Sinai Medical Center

Los Angeles

CA

Disclosures

MOG has been reimbursed for one-time participation in an advisory board for Nestle Health Science on the topic of exocrine pancreatic dysfunction. MOG is an author of a number of references cited in this topic.

Peer reviewers

Antoni Duleba, MD

Professor

Department of Obstetrics and Gynecology

University of California Davis

Sacramento

CA

Disclosures

AD declares that he has no competing interests.

Richard S. Legro, MD

Professor

Department of Obstetrics and Gynecology

Penn State Hershey College of Medicine

Hershey

PA

Disclosures

RSL has been reimbursed by Serono for attending a medical conference and received a lecture fee, and has consulted for Ferring. He has received research funding from the NIH, the Commonwealth of Pennsylvania, and Parke Davis. He is an author of a number of references cited in this topic.

Cornelis B. (Nils) Lambalk, MD, PhD

Gynaecologist/Fertility Specialist

Division of Reproductive Medicine

Department of Obstetrics and Gynaecology

VU University Medical Centre

Amsterdam

The Netherlands

Disclosures

CBL declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Azziz R, Carmina E, Chen Z, et al. Polycystic ovary syndrome. Nat Rev Dis Primers. 2016 Aug 11;2:16057. Abstract

Teede HJ, Tay CT, Laven JJE, et al. Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome. J Clin Endocrinol Metab. 2023 Sep 18;108(10):2447-69.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
  • Síndrome do ovário policístico images
  • Differentials

    • Deficiência de 21-hidroxilase
    • Disfunção tireoidiana
    • Hiperprolactinemia
    More Differentials
  • Guidelines

    • International evidence-based guideline for the assessment and management of polycystic ovary syndrome
    • Practice bulletin: polycystic ovary syndrome
    More Guidelines
  • Patient information

    Síndrome do ovário policístico: quais tratamentos funcionam?

    Síndrome do ovário policístico: o que é?

    More Patient information
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