Summary
Definition
History and exam
Key diagnostic factors
- presença de fatores de risco
- mulheres em idade fértil
- menstruação irregular
- infertilidade
- hirsutismo
Other diagnostic factors
- acne
- sobrepeso ou obesidade
- hipertensão
- queda de cabelos
- pele oleosa ou sudorese excessiva
- acantose nigricans
Risk factors
- história familiar de síndrome do ovário policístico (SOPC)
- adrenarca prematura
- obesidade
- baixo peso ao nascer
- exposição do feto ao androgênio
- interferências endócrinas causadas pelo ambiente
Diagnostic investigations
1st investigations to order
- 17-hidroxiprogesterona sérica
- prolactina sérica
- hormônio estimulante da tireoide sérico
- teste oral de tolerância à glicose
- perfil lipídico em jejum
Investigations to consider
- testosterona sérica total e livre
- sulfato de desidroepiandrosterona sérico (DHEA-S)
- androstenediona sérica
- ultrassonografia pélvica
- hormônio antimülleriano sérico
- monitoramento da temperatura basal do corpo
- medição do progesterona na fase lútea
- LH e hormônio folículo-estimulante (FSH) séricos
- hemoglobina A1c ou glicemia de jejum
Treatment algorithm
com infertilidade e fertilidade desejada
não desejam a fertilidade atualmente
Contributors
Authors
Mark O. Goodarzi, MD, PhD
Division of Endocrinology, Diabetes & Metabolism
Eris M. Field Chair in Diabetes Research
Professor of Medicine
Cedars-Sinai Medical Center
Los Angeles
CA
Disclosures
MOG has been reimbursed for one-time participation in an advisory board for Nestle Health Science on the topic of exocrine pancreatic dysfunction. MOG is an author of a number of references cited in this topic.
Peer reviewers
Antoni Duleba, MD
Professor
Department of Obstetrics and Gynecology
University of California Davis
Sacramento
CA
Disclosures
AD declares that he has no competing interests.
Richard S. Legro, MD
Professor
Department of Obstetrics and Gynecology
Penn State Hershey College of Medicine
Hershey
PA
Disclosures
RSL has been reimbursed by Serono for attending a medical conference and received a lecture fee, and has consulted for Ferring. He has received research funding from the NIH, the Commonwealth of Pennsylvania, and Parke Davis. He is an author of a number of references cited in this topic.
Cornelis B. (Nils) Lambalk, MD, PhD
Gynaecologist/Fertility Specialist
Division of Reproductive Medicine
Department of Obstetrics and Gynaecology
VU University Medical Centre
Amsterdam
The Netherlands
Disclosures
CBL declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
Azziz R, Carmina E, Chen Z, et al. Polycystic ovary syndrome. Nat Rev Dis Primers. 2016 Aug 11;2:16057. Abstract
Teede HJ, Tay CT, Laven JJE, et al. Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome. J Clin Endocrinol Metab. 2023 Sep 18;108(10):2447-69.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Deficiência de 21-hidroxilase
- Disfunção tireoidiana
- Hiperprolactinemia
More DifferentialsGuidelines
- International evidence-based guideline for the assessment and management of polycystic ovary syndrome
- Practice bulletin: polycystic ovary syndrome
More GuidelinesPatient information
Síndrome do ovário policístico: quais tratamentos funcionam?
Síndrome do ovário policístico: o que é?
More Patient information
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