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Transtorno esquizoafetivo

  • Descripción general
  • Teoría
  • Diagnóstico
  • Manejo
  • Seguimiento
  • Recursos
Última revisión: 12 Oct 2025
Última actualización: 27 Jul 2022

Resumen

Definición

Anamnesis y examen

Principales factores de diagnóstico

  • sintomas positivos
  • sintomas negativos
  • distúrbios de percepção
  • delírios
  • perturbações nas emoções
  • afeto incongruente
  • distúrbios de fluxo e forma de pensamento
  • anormalidades cognitivas
  • sintomas deficitários
  • episódios depressivos maiores
  • episódios maníacos
Todos los datos

Otros factores de diagnóstico

  • deficit neurológico
  • história familiar
  • comprometimento funcional
  • distúrbios de comportamento
Todos los datos

Factores de riesgo

  • história familiar de esquizofrenia
  • uso de substâncias
  • idade do pai no nascimento do paciente
  • estresse psicológico
  • ambiente
Todos los datos

Pruebas diagnósticas

Primeras pruebas diagnósticas para solicitar

  • exame de urina para detecção de drogas
  • rastreamento de infecções sexualmente transmissíveis
  • hemograma completo
  • testes da função tireoidiana
Todos los datos

Pruebas diagnósticas que deben considerarse

  • exames laboratoriais para excluir causas orgânicas
  • tomografia computadorizada/ressonância nuclear magnética (TC/RNM) de crânio
  • eletroencefalograma (EEG)
Todos los datos

Algoritmo de tratamiento

Agudo

episódio psicótico agudo

En curso

transtorno de episódios múltiplos

Colaboradores

Autores

Adrian Preda, MD
Adrian Preda

Professor of Clinical Psychiatry

Department of Psychiatry and Human Behavior

University of California, Irvine School of Medicine

Irvine

CA

Divulgaciones

AP was paid for consultancy work for GLG and Guidepoint.

Robert G. Bota, MD
Robert G. Bota

Associate Clinical Professor of Psychiatry

University of California

Irvine

CA

Divulgaciones

RGB declares that he has no competing interests.

Agradecimientos

Dr Adrian Preda and Dr Robert G. Bota would like to gratefully acknowledge Dr Bao-Nhan Benjamin Nguyen, who contributed to the updating of this topic.

Disclosures

BN declares that he has no competing interests.

Peer reviewers

Kemal Sagduyu, MD

Professor of Psychiatry

University of Missouri Kansas City

Kansas City

MO

Disclosures

KS declares that he has no competing interests.

William T. Regenold, MDCM

Associate Professor of Psychiatry

University of Maryland School of Medicine

Baltimore

MD

Disclosures

WTR declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Abrams DJ, Rojas DC, Arciniegas DB. Is schizoaffective disorder a distinct categorical diagnosis? A critical review of the literature. Neuropsychiatr Dis Treat. 2008 Dec;4(6):1089-109.Full text  Abstract

Harrow M, Grossman LS, Herbener ES, et al. Ten-year outcome: patients with schizoaffective disorders, schizophrenia, affective disorders and mood-incongruent psychotic symptoms. Br J Psychiatry. 2000 Nov;177:421-6.Full text  Abstract

Cheniaux E, Landeira-Fernandez J, Versiani M. The diagnoses of schizophrenia, schizoaffective disorder, bipolar disorder and unipolar depression: interrater reliability and congruence between DSM-IV and ICD-10. Psychopathology. 2009;42(5):293-8. Abstract

Jäger M, Haack S, Becker T, et al. Schizoaffective disorder: an ongoing challenge for psychiatric nosology. Eur Psychiatry. 2011 Apr;26(3):159-65. Abstract

Turner DT, van der Gaag M, Karyotaki E, et al. Psychological interventions for psychosis: a meta-analysis of comparative outcome studies. Am J Psychiatry. 2014 May;171(5):523-38. Abstract

National Institute for Health and Care Excellence. Psychosis and schizophrenia in adults: prevention and management. March 2014 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

  • Differentials

    • Esquizofrenia
    • Transtorno psicótico induzido por substâncias
    • Demência com psicose
    More Differentials

  • Guidelines

    • International statistical classification of diseases and related health problems, 11th revision (ICD-11)
    • Diagnostic and statistical manual, 5th edition, text revision (DSM-5-TR)
    More Guidelines

  • Patient information

    Transtorno esquizoafetivo

    More Patient information
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