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Ambliopia

Last reviewed: 6 Nov 2025
Last updated: 17 Sep 2025

Summary

Definition

History and exam

Key diagnostic factors

  • presença de fatores de risco
  • assintomático
  • acuidade visual subnormal para a idade em um ou em ambos os olhos
  • falha no teste de "fixar e seguir" em bebês
  • reflexo vermelho anormal
Full details

Other diagnostic factors

  • reflexo da luz na córnea assimétrico
  • resposta desigual à oclusão alternada dos olhos
  • teste de cobrir/descobrir anormal
  • visão turva
  • fadiga ocular
  • nistagmo congênito
  • exame da pupila anormal
  • exame ocular externo anormal
Full details

Risk factors

  • idade <9 anos
  • estrabismo
  • erros de refração altos (não corrigidos)
  • opacidade dos meios
  • ptose grave ou oclusão prolongada de um ou de ambos os olhos
  • prematuridade
  • história familiar de ambliopia ou estrabismo
  • atraso do desenvolvimento
  • anormalidade estrutural da retina ou do vítreo
Full details

Diagnostic tests

1st tests to order

  • teste do reflexo vermelho binocular (teste de Brückner)
  • testes de acuidade visual (monocular)
  • teste de estereopsia/visão binocular
  • avaliação de fixação, alinhamento ocular e motilidade ocular
  • exame do segmento anterior usando uma lâmpada de fenda
  • fundoscopia dilatada
  • retinoscopia cicloplégica
Full details

Emerging tests

  • potenciais evocados visuais (PEVs)

Treatment algorithm

ONGOING

ambliopia sem privação de forma

ambliopia por privação de forma

ambliopia refratária (paciente não observante)

Contributors

Authors

Irene Gottlob, MD

Professor of Ophthalmology

Cooper University Health Care

Cooper Medical School

Rowan University

Glassboro

NJ

Disclosures

IG declares that she has no competing interests. IG is an author of references cited in this topic.

Gail Maconachie, PhD, BMedSci

Lecturer

School of Allied Health Professions, Nursing and Midwifery,

Faculty of Health

University of Sheffield

UK

Disclosures

GM declares that she has no competing interests. GM is an author of a reference cited in this topic.

Eleni Papageorgiou, MD, PhD

Consultant in Pediatric Ophthalmology, Strabismus and Neuro-Ophthalmology

Department of Ophthalmology

University Hospital of Larissa

Larissa

Greece

Disclosures

EP declares that she has no competing interests.

Acknowledgements

Dr Irene Gottlob, Dr Gail Maconachie, and Dr Eleni Papageorgiou would like to gratefully acknowledge Dr Tina Rutar, the previous contributor to this topic

Disclosures

TR declared that she had no competing interests.

Peer reviewers

Mary C. Whitman, MD, PhD

Assistant Professor of Ophthalmology

Boston Children’s Hospital

Harvard Medical School

Boston

MA

Disclosures

MCW declares that she has no competing interests.

Nathan Cheung, OD, FAAO

Assistant Professor of Ophthalmology

Duke University

Durham

NC

Disclosures

NC declares that he has no competing interests.

Michael Clarke, FRCS, FCOphth

Reader in Ophthalmology

Newcastle University

Newcastle

UK

Disclosures

MC has received NHS research grants of more than 6 figures USD. MC is an author of a number of references cited in this topic.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

American Academy of Ophthalmology. Amblyopia PPP 2022 - updated 2024. Dec 2022 [internet publication].Full text

Hutchinson AK, Morse CL, Hercinovic A, et al. Pediatric eye evaluations preferred practice pattern. Ophthalmology. 2023 Mar;130(3):P222-70.Full text  Abstract

US Preventive Services Task Force; Grossman DC, Curry SJ, Owens DK, et al. Vision screening in children ages 6 months to 5 years: US Preventive Services Task Force Recommendation Statement. JAMA. 2017 Sep 5;318(9):836-44.Full text  Abstract

American Academy of Ophthalmology. Pediatric ophthalmology/strabismus summary benchmarks - 2024. Dec 2024 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
  • Ambliopia images
  • Differentials

    • Erros de refração sem ambliopia
    • Comprometimento funcional visual
    • Patologia do sistema nervoso central afetando as vias visuais
    More Differentials
  • Guidelines

    • Amblyopia preferred practice pattern
    • Pediatric ophthalmology/strabismus summary benchmarks
    More Guidelines
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