Резюме
Определение
Анамнез и осмотр
Ключевые диагностические факторы
- presença de fatores de risco
- idade >40 anos
- rouquidão
- disfagia
- odinofagia (deglutição dolorosa)
- linfadenopatia cervical
- massa supraglótica ou glótica
- eritroplasia lesional, ulceração, necrose ou sangramento
- sinais de obstrução das vias aéreas
- instabilidade hemodinâmica
Другие диагностические факторы
- faringite
- otalgia
- efusão no ouvido médio
- estridor
- perda de peso ou caquexia
- sofrimento geral
- massas orofaríngeas ou leucoplasia
- perda de crepitação laríngea
- crescimentos na parótida e tireoide
- murmúrio vesicular diminuído
Факторы риска
- tabagismo
- uso de álcool >8 unidades/dia
- história de radioterapia
- etnia negra
- sexo masculino
- displasia das pregas vocais
- Doença do refluxo gastroesofágico (DRGE)
- acloridria
- história familiar de câncer laríngeo
- exposição ao Agente Laranja
- infecção por papilomavírus humano (HPV)
Диагностические исследования
Исследования, которые показаны в первую очередь
- tomografia computadorizada (TC) de pescoço com contraste
- TC de tórax com ou sem contraste
- RNM com e sem contraste
- aspiração por agulha fina (AAF) da massa cervical
- laringoscopia com fibra óptica flexível
Исследования, проведение которых нужно рассмотреть
- videoestroboscopia rígida
- laringoscopia direta e rígida
- teste de imuno-histoquímica
- biópsia da laringe
- PET/TC do corpo inteiro
- endoscopia de fluorescência
Алгоритм лечения
glótico ou supraglótico
subglótico
tratamento ineficaz/inadequado
Составители
Авторы
Matthew Pierce, MD
Otolaryngologist
Otolaryngology, Head and Neck Division
MedStar Washington Hospital Center
Georgetown University
Washington
DC
Раскрытие информации
MP declares that he has no competing interests.
Выражение благодарностей
Dr Matthew Pierce would like to gratefully acknowledge Dr Scott V. Larson, Dr Hari Deshpande, Dr Elina Kari, Dr Amy Chen, and the late Dr Clarence Sasaki, previous contributors to this topic.
Раскрытие информации
SVL, HD, EK, and AC declare that they have no competing interests.
Рецензенты
Alfio Ferlito, MD, DLO, DPath, FRCSEd
Director
Department of Surgical Sciences
Professor and Chairman
ENT Clinic
University of Udine
Udine
Italy
Раскрытие информации
AF declares that he has no competing interests.
Steven J. Charous, MD, FACS
Assistant Professor
Department of Otolaryngology
Rush University Medical Center
Chicago
IL
Раскрытие информации
SJC declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Список литературы
Основные статьи
National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: head and neck cancers [internet publication].Полный текст
Forastiere AA, Ismaila N, Lewin JS, et al. Use of larynx-preservation strategies in the treatment of laryngeal cancer: American Society of Clinical Oncology clinical practice guideline update. J Clin Oncol. 2018 Apr 10;36(11):1143-69.Полный текст Аннотация
American College of Radiology. ACR Appropriateness Criteria: retreatment of recurrent head and neck cancer after prior definitive radiation. 2014 [internet publication].Полный текст
Статьи, указанные как источники
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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