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Последний просмотренный: 6 Apr 2026
Last updated: 22 Oct 2025

Резюме

Определение

Анамнез и осмотр

Ключевые диагностические факторы

  • presença de fatores de risco
  • tosse
  • dispneia
  • fadiga crônica
  • artralgia
  • sibilância
  • roncos
  • linfadenopatia
  • fotofobia
  • olho dolorido e vermelho
  • visão turva
  • eritema nodoso
  • lúpus pérnio
  • nódulos conjuntivais
  • paralisia facial
Полная информация

Другие диагностические факторы

  • ausência de história de exposição a berílio
  • dor na parede torácica
  • hemoptise
  • perda de peso
  • febre baixa
  • arritmias
  • bloqueio atrioventricular
  • hepatomegalia
  • cefaleia
  • convulsões
  • sintomas e sinais de lesão hipofisária
Полная информация

Факторы риска

  • idade 20-50 anos
  • história familiar de sarcoidose
  • origem escandinava
  • sexo feminino
  • não fumantes
  • ascendência negra
  • ascendência negra: uveíte
  • origem porto-riquenha: lupus pernio
  • Origem europeia: eritema nodoso
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • radiografia torácica
  • Hemograma completo
  • ureia sérica
  • creatinina sérica
  • enzimas hepáticas
  • cálcio sérico
  • testes de função pulmonar
  • eletrocardiograma (ECG)
  • exame oftalmológico
  • teste de liberação de gamainterferona
Полная информация

Исследования, проведение которых нужно рассмотреть

  • enzima conversora da angiotensina (ECA) sérica
  • TC do tórax
  • aspiração por agulha transbrônquica guiada por ultrassonografia endobrônquica
  • lavagem broncoalveolar (LBA)
  • biópsia de pele
  • cálcio urinário de 24 horas
  • cintigrafia com gálio-67
  • vitamina D
  • RNM
  • tomografia por emissão de pósitrons (PET) com (18)F-fluordesoxiglucose (FDG)
Полная информация

Неотложные исследования

  • PET com 3'-desoxi-3'-[18F]-fluorotimidina (FLT)
  • PET-CT com 4'-[metil-11C]-tiotimidina

Алгоритм лечения

Острый

em insuficiência respiratória aguda e incapaz de tolerar ingestão oral

em insuficiência respiratória aguda mas capaz de tolerar ingestão oral

ПРОДОЛЖЕНИЕ

doença pulmonar

doença cutânea

doença ocular

doença cardiovascular

envolvimento do sistema nervoso central ou do sistema nervoso periférico

doença renal

Составители

Авторы

Muthiah P. Muthiah, MD, FCCP

Acting Chief of Pulmonary, Critical Care & Sleep Medicine

VA Medical Center, Memphis

Professor & Vice Chair of Medicine

University of Tennessee Health Science Center

Memphis

TN

Раскрытие информации

MPM declares that he has no competing interests.

Amr El Gamal, MD, FCCP

Pulmonary and Critical Care

Medical Service

VA Medical Center

Martinsburg

Assistant Professor of Medicine

West Virginia University

Morgantown

WV

Раскрытие информации

AEG declares that he has served as a reviewer for the American Physician Institute.

Рецензенты

George Swingler, MD

Professor

School of Child and Adolescent Health

Red Cross Children's Hospital

University of Cape Town

Rondebosch

Cape Town

South Africa

Раскрытие информации

GS declares that he has no competing interests.

Kyle Hogarth, MD, FCCP

Assistant Professor of Medicine

Department of Medicine

Section of Pulmonary and Critical Care

University of Chicago

Chicago

IL

Раскрытие информации

KH declares that he has no competing interests.

Marc Judson, MD

Chief

Division of Pulmonary and Critical Care Medicine

AMC Pulmonary and Critical Care Medicine

Albany

NY

Раскрытие информации

MJ declares that he has no competing interests.

Nadera Sweiss, MD

Assistant Professor of Medicine

Section of Rheumatology

Department of Medicine

University of Chicago

Chicago

IL

Раскрытие информации

NS declares that she has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Основные статьи

American Thoracic Society. Statement on sarcoidosis. Joint Statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. Am J Respir Crit Care Med. 1999 Aug;160(2):736-55.Полный текст  Аннотация

Thillai M, Atkins CP, Crawshaw A, et al. BTS clinical statement on pulmonary sarcoidosis. Thorax. 2021 Jan;76(1):4-20.Полный текст  Аннотация

Crouser ED, Maier LA, Wilson KC, et al. Diagnosis and detection of sarcoidosis. An official American Thoracic Society clinical practice guideline. Am J Respir Crit Care Med. 2020 Apr 15;201(8):e26-51.Полный текст  Аннотация

Cheng RK, Kittleson MM, Beavers CJ, et al. Diagnosis and management of cardiac sarcoidosis: a scientific statement from the American Heart Association. Circulation. 2024 May 21;149(21):e1197-216.Полный текст  Аннотация

Baughman RP, Valeyre D, Korsten P, et al. ERS clinical practice guidelines on treatment of sarcoidosis. Eur Respir J. 2021 Dec;58(6):2004079.Полный текст  Аннотация

Статьи, указанные как источники

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