Resumo
Differentials
Common
- Esquizofrenia
- Transtorno esquizoafetivo
- Transtorno psicótico breve
- Transtorno esquizofreniforme
- Depressão com características psicóticas
- Transtorno bipolar
- Transtorno delirante
- Bebidas alcoólicas
- Síndrome de abstinência
- Cocaína
- Cannabis
- Anfetaminas
- Fenciclidina
- Inalantes (solventes, aerossóis, gases, nitritos)
- Dextrometorfano
- Demência
- Deficiência crônica de tiamina (psicose de Korsakoff)
- Porfiria hepática aguda
Uncommon
- Sintomas delirantes em parceiro de indivíduo com transtorno delirante (folie à deux)
- Toxicidade por organofosforados
- Anticolinérgicos
- Agonistas dopaminérgicos
- Outros medicamentos prescritos ou de venda livre
- Toxicidade por metais pesados
- Lesão cerebral traumática
- Tumor cerebral
- Epilepsia
- Esclerose múltipla
- Encefalite (infecciosa ou autoimune)
- vírus da imunodeficiência humana (HIV)
- Neurossífilis
- Delirium com psicose
- Deficiência de vitamina B12
- Deficiência de folato
- Deficiência de niacina
- Síndrome de Cushing
- Disfunção tireoidiana
- Timoma
- Hiperparatireoidismo
- Cerebrite lúpica
- Doença de Wilson
- Doença do armazenamento lisossomal
- Homocistinúria
- Leucodistrofia metacromática
- Síndrome de Klinefelter
- Síndrome de DiGeorge
- Síndrome de Prader-Willi
Contributors
Authors
Adrian Preda, MD
Professor of Clinical Psychiatry
Department of Psychiatry and Human Behavior
University of California, Irvine School of Medicine
Irvine
CA
Disclosures
AP declares that he has no competing interests.
Graham Blackman, MBChB, MRCPsych
Department of Psychosis Studies
Institute of Psychiatry, Psychology and Neuroscience
King’s College London
London
UK
Disclosures
GB declares that he has no competing interests. He is an author of publications cited in this topic.
Acknowledgements
Dr Adrian Preda and Dr Graham Blackman would like to gratefully acknowledge Dr Karen A. Graham and Dr Diana O. Perkins, previous contributors to this topic.
Disclosures
KAG declares that she has no competing interests. DOP has served as a consultant on antipsychotic medications for Genentech, Janssen, Lundbeck, Otsuka, and Sunovion. The University of North Carolina at Chapel Hill received compensation for research and consulting work by DOP from Genentech, the NIH, Research Triangle Institute, and the State of North Carolina; the university has also been awarded a patent for isolation of pluripotent stem cells from human tissues, with Diana Perkins listed as one of the inventors. DOP has received royalties for the textbook Schizophrenia, published by the American Psychiatric Association Press.
Peer reviewers
Philip McGuire, MBChB, MD, PhD, FRCPsych
Department of Psychosis Studies
Institute of Psychiatry, Psychology and Neuroscience
King’s College London
London
UK
Disclosures
PM has been reimbursed by manufacturers of antipsychotic drugs for consultancy and speaking at conferences. PM has received grant funding for research and to support scientific conferences.
Vinod H. Srihari, MD
Assistant Professor of Psychiatry
Yale University School of Medicine
Connecticut Mental Health Center
New Haven
CT
Disclosures
VHS declares that he has no competing interests.
References
Key articles
American Psychiatric Association. Diagnostic and statistical manual of mental disorders, fifth edition, text revision (DSM-5-TR). Washington, DC: American Psychiatric Association; 2022.
National Institute for Health and Care Excellence. Psychosis and schizophrenia in adults: prevention and management. Mar 2014 [internet publication].Full text
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Guidelines
- ACR appropriateness criteria® altered mental status, coma, delirium, and psychosis 2024
- Diagnostic and statistical manual of mental disorders, fifth edition, text revision (DSM-5-TR)
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