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Arterite de Takayasu

Última revisão: 13 Aug 2025
Última atualização: 10 Jan 2025

Resumo

Definição

Анамнез и осмотр

Ключевые диагностические факторы

  • presença de fatores de risco
  • claudicação dos membros superiores ou inferiores
  • ausência de pulso(s)
  • pressões arteriais desiguais
  • sopros vasculares
  • febre baixa
Полная информация

Другие диагностические факторы

  • ataque isquêmico transitório (AIT)
  • mialgia
  • artralgia
  • perda de peso
  • fadiga
  • tontura no esforço físico dos membros superiores
  • hipertensão
  • acidente vascular cerebral (AVC)
  • dor torácica
  • dor abdominal
  • diarreia
  • dispneia
  • hemoptise
  • sudorese noturna
  • vertigem
  • síncope
  • cefaleia
  • sopro cardíaco
  • sintomas visuais
  • eritema nodoso
  • pioderma gangrenoso
Полная информация

Факторы риска

  • predisposição genética
  • sexo feminino
  • idade <40 anos
  • etnicidade asiática
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • velocidade de hemossedimentação (VHS)
  • proteína C-reativa
  • angiotomografia (ATG)
  • angiografia por ressonância magnética (ARM)
Полная информация

Исследования, проведение которых нужно рассмотреть

  • ultrassonografia com Doppler
  • tomografia por emissão de pósitrons com fluordesoxiglucose radiomarcada (PET-FDG)
Полная информация

Алгоритм лечения

Острый

todos os pacientes

Составители

Авторы

Kenneth J. Warrington, MD
Kenneth J. Warrington

Professor of Medicine

Mayo Clinic College of Medicine

Rochester

MN

Раскрытие информации

KJW declares that he has received clinical trial support from Eli Lilly, BMS, and Kiniksa. He has received consulting fees and honoraria from Amgen and Sanofi. KJW is an author of a number of references cited in this topic.

Выражение благодарностей

Dr Kenneth J. Warrington would like to gratefully acknowledge Dr Steven R. Ytterberg and Dr Eric L. Matteson, previous contributors to this topic.

Раскрытие информации

SRY declares that he was a sub-awardee of a grant from the US Food and Drug Administration for a pilot study of abatacept, a treatment for Takayasu's arteritis. SRY is also a member of the steering committee at the Vasculitis Clinical Research Committee. ELM declares that he has no competing interests.

Рецензенты

Loic P. Guillevin, MD

Internal Medicine

Hopital Cochin-Paris University

St-Jacques

Paris

France

Раскрытие информации

LPG declares that he has no competing interests.

Gene G. Hunder, MD

Department of Medicine

Division of Rheumatology

Mayo Clinic

Rochester

MN

Раскрытие информации

GGH is an author of a reference cited in this topic. GGH declares that he has no other competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

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Основные статьи

Weyand CM, Goronzy JJ. Medium- and large-vessel vasculitis. N Engl J Med. 2003 Jul 10;349(2):160-9. Аннотация

Kerr GS. Takayasu's arteritis. Rheum Dis Clin North Am. 1995 Nov;21(4):1041-58. Аннотация

Maz M, Chung SA, Abril A, et al. 2021 American College of Rheumatology/Vasculitis Foundation guideline for the management of giant cell arteritis and Takayasu arteritis. Arthritis Rheumatol. 2021 Aug;73(8):1349-65.Полный текст  Аннотация

Pugh D, Karabayas M, Basu N, et al. Large-vessel vasculitis. Nat Rev Dis Primers. 2022 Jan 6;7(1):93.Полный текст  Аннотация

Isselbacher EM, Preventza O, et al. 2022 ACC/AHA guideline for the diagnosis and management of aortic disease: a report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. J Am Coll Cardiol. 2022 Dec 13;80(24):e223-393. Аннотация

Grayson PC, Ponte C, Suppiah R, et al. 2022 American College of Rheumatology/EULAR classification criteria for Takayasu arteritis. Ann Rheum Dis. 2022 Dec;81(12):1654-60.Полный текст  Аннотация

Статьи, указанные как источники

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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