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Cefaleia enxaquecosa em adultos

Last reviewed: 17 Aug 2025
Last updated: 07 Mar 2025

Summary

Definition

History and exam

Key diagnostic factors

  • presença de fatores de risco
  • cefaleia prolongada
  • náuseas e/ou vômitos
  • capacidade reduzida de desempenhar atividades
  • piora na cefaleia com a prática de atividades
  • sensibilidade à luz
  • sensibilidade ao ruído
  • unilateral
  • sensação pulsátil
  • aura
Full details

Risk factors

  • história familiar de enxaqueca
  • sexo feminino
  • obesidade
  • eventos vitais estressantes
  • uso excessivo de medicamentos
  • distúrbios do sono
  • condição socioeconômica baixa
  • alergias ou asma
  • hipotireoidismo
Full details

Diagnostic tests

1st tests to order

  • diagnóstico clínico
Full details

Tests to consider

  • velocidade de hemossedimentação (VHS)
  • proteína C-reativa
  • punção lombar (PL)
  • cultura do líquido cefalorraquidiano (LCR)
  • ressonância nuclear magnética (RNM) cranioencefálica
  • tomografia computadorizada (TC) do crânio
  • angiografia
Full details

Treatment algorithm

INITIAL

apresenta-se ao pronto-socorro com enxaqueca persistente

ACUTE

sintomas leves: não gestante

sintomas moderados a graves: não gestante

gestante

ONGOING

sintomas recorrentes frequentes, graves/incapacitantes, não relacionados ao ciclo menstrual: não gestante

sintomas recorrentes frequentes, graves/incapacitantes, relacionados ao ciclo menstrual: não gestante

sintomas graves/incapacitantes recorrentes frequentes: gestante

Contributors

Authors

Timothy A. Collins, MD

Associate Professor of Neurology

Chief

Headache Division

Department of Neurology

Duke University Medical Center

Durham

NC

Disclosures

TAC provides expert testimony for legal cases regarding headache disorders and treatment (approximately one or two cases per year). TAC is an author of several references cited in this topic.

Acknowledgements

Dr Timothy Collins would like to gratefully acknowledge Dr Ann Donnelly, the previous contributor to this topic.

Disclosures

AD declares that she has no competing interests.

Peer reviewers

Anne Walling, MD

Professor

Family and Community Medicine

University of Kansas School of Medicine

Wichita

KS

Disclosures

AW declares that she has no competing interests.

Marc S. Husid, MD

Director

Walton Headache Center

Augusta

GA

Disclosures

MSH declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Ailani J, Burch RC, Robbins MS, et al. The American Headache Society consensus statement: update on integrating new migraine treatments into clinical practice. Headache. 2021 Jul;61(7):1021-39.Full text  Abstract

Eigenbrodt AK, Ashina H, Khan S, et al. Diagnosis and management of migraine in ten steps. Nat Rev Neurol. 2021 Aug;17(8):501-14.Full text  Abstract

Becker WJ, Findlay T, Moga C, et al. Guideline for primary care management of headache in adults. Can Fam Physician. 2015 Aug;61(8):670-9.Full text  Abstract

Worthington I, Pringsheim T, Gawel MJ, et al. Canadian Headache Society Guideline: acute drug therapy for migraine headache. Can J Neurol Sci. 2013 Sep;40(5 suppl 3):S1-S80.Full text  Abstract

VanderPluym JH, Halker Singh RB, Urtecho M, et al. Acute treatments for episodic migraine in adults: a systematic review and meta-analysis. JAMA. 2021 Jun 15;325(23):2357-69.Full text  Abstract

Orr SL, Friedman BW, Christie SC, et al. Management of adults with acute migraine in the emergency department: the American Headache Society evidence assessment of parenteral pharmacotherapies. Headache. 2016 Jun;56(6):911-40.Full text  Abstract

Silberstein SD, Holland S, Freitag F, et al; Quality Standards Subcommittee of the American Academy of Neurology and the American Headache Society. Evidence-based guideline update: pharmacologic treatment for episodic migraine prevention in adults. Neurology. 2012 Apr 24;78(17):1337-45.Full text  Abstract

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
  • Differentials

    • Cefaleia tensional
    • Cefaleia em salvas
    • Cefaleia por uso excessivo de medicamentos
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  • Guidelines

    • Prevention of episodic migraine headache using pharmacologic treatments in outpatient settings: a clinical guideline from the American College of Physicians
    • The international classification of headache disorders, 3rd edition
    More Guidelines
  • Patient information

    Enxaqueca: perguntas a fazer ao seu médico

    Enxaqueca

    More Patient information
  • Videos

    Punção lombar diagnóstica em adultos: vídeo de demonstração

    Canulação venosa periférica – Vídeo de demonstração

    More videos
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