小结
定义
病史和体格检查
关键诊断因素
- history of residence in, or recent travel to, endemic area
- lack of yellow fever immunization
- history of mosquito bite
- fever
- constitutional symptoms
- conjunctival injection
- relative bradycardia (Faget sign)
- biphasic illness
- hemorrhagic diathesis
- signs of renal failure
- signs of hepatic failure
- jaundice
其他诊断因素
- hypotension
- abdominal pain, vomiting, and lethargy
危险因素
- residence in, or recent travel to, endemic area
- lack of immunization
- mosquito bite
- travel during rainy and early dry seasons
诊断性检查
首要检查
- CBC
- liver function tests
- coagulation screen
- reverse transcription polymerase chain reaction (RT-PCR)
- serology
需考虑的检查
- ECG
- histopathology
新兴检查
- virus isolation
- isothermal nucleic acid amplification assays
治疗流程
unidentified viral hemorrhagic fever
confirmed yellow fever
撰稿人
作者
William A. Messer, MD, PhD
Associate Professor of Medicine
Department of Molecular Microbiology and Immunology
Division of Infectious Diseases
Oregon Health & Science University
Portland
OR
利益声明
WAM declares that he has no competing interests.
鸣谢
Dr William A. Messer would like to gratefully acknowledge Dr Philip A. Yeon and Dr Helmut Albrecht, previous contributors to this topic.
Disclosures
PAY and HA declares that he has no competing interests.
同行评议者
Carlos Franco-Paredes, MD, MPH
Assistant Professor
Emory University
TravelWell Clinic
Emory University Hospital Midtown
Atlanta
GA
利益声明
CFP declares that he has no competing interests.
Andrea K. Boggild, MSc, MD, DTMH, FRCPC
Clinical Assistant
Tropical Diseases Unit
Division of Infectious Diseases
Department of Medicine
Toronto General Hospital
University Health Network
Toronto
Canada
利益声明
AKB declares that she has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
参考文献
关键文献
World Health Organization. Yellow fever: fact sheet. May 2023 [internet publication].全文
Staples JE, Bocchini JA Jr, Rubin L; Centers for Disease Control and Prevention (CDC). Yellow fever vaccine booster doses: recommendations of the Advisory Committee on Immunization Practices, 2015. MMWR Morb Mortal Wkly Rep. 2015;64:647-650.全文 摘要
Pan American Health Organization; World Health Organization. Laboratory diagnosis of yellow fever virus infection. September 2018 [internet publication].全文
参考文献
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

鉴别诊断
- Dengue fever
- Malaria
- Zika virus infection
更多 鉴别诊断指南
- CDC Yellow Book: health information for international travel - yellow fever
- Laboratory diagnosis of yellow fever virus infection
更多 指南Conectar-se ou assinar para acessar todo o BMJ Best Practice
O uso deste conteúdo está sujeito ao nosso aviso legal