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Celulitis y erisipelas

Last reviewed: 20 Aug 2025
Last updated: 10 Jun 2025

Summary

Definition

History and exam

Key diagnostic factors

  • presencia de factores de riesgo
  • molestias en la piel
  • eritema macular
  • ruptura de la barrera cutánea
  • eritema elevado de color rojo brillante con márgenes claramente delimitados (erisipela)
  • riesgo de infección por Staphylococcus aureus resistente a la meticilina (SARM)
Full details

Other diagnostic factors

  • antecedentes de diabetes
  • pródromo general
  • linfangitis/linfadenopatía regional
  • Puerto de entrada identificable
  • antecedentes de compromiso inmunológico
  • exposición poco habitual (agua salada o dulce, mordedura)
Full details

Risk factors

  • diabetes
  • insuficiencia venosa y edema crónico de la pierna
  • dermatosis
  • linfedema
  • episodio anterior de celulitis
  • alteraciones en la membrana de los dedos del pie
  • consumo de drogas ilícitas por vía intravenosa
  • sobrepeso
Full details

Diagnostic investigations

1st investigations to order

  • hemograma completo (HC)
  • cultivo de foco purulento y procedimientos de diagnóstico molecular
Full details

Investigations to consider

  • aspiración cutánea con cultivo y procedimientos de diagnóstico molecular
  • hemocultivo
  • biopsia de piel
  • radiografía simple
  • ultrasonido
  • exploración por tomografía computarizada (TC)
  • resonancia magnética (IRM)
Full details

Treatment algorithm

ACUTE

leve

moderado

grave

ONGOING

fracaso del tratamiento

pacientes con recidivas frecuentes

Contributors

Authors

Arash Mostaghimi, MD, MPA, MPH

Assistant Professor of Dermatology

Harvard Medical School

Director, Inpatient Consultation Service

Department of Dermatology

Brigham and Women’s Hospital

Boston

MA

Disclosures

AM has received fees or honoraria for consulting from hims and hers, AbbVie, Sun Pharma, Pfizer, Digital Diagnostics, Lilly, Equillium, ASLAN, Boehringer Ingelheim, Figure 1, Dermatheory, Olaplex, and Legacy Healthcare.

Acknowledgements

Dr Arash Mostaghimi would like to gratefully acknowledge Dr Matthew C. Robinson, the previous contributor to this topic.

Disclosures

MCR declares that he has no competing interests.

Peer reviewers

Robert W. Bradsher, MD

Ebert Professor of Medicine

Director

Division of Infectious Diseases

University of Arkansas for Medical Sciences

Little Rock

AR

Disclosures

RWB declares that he has no competing interests.

Jorg Ruhe, MD, MPH

Assistant Attending

Beth Israel Medical Center

New York

NY

Disclosures

JR declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

References

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Key articles

Raff AB, Kroshinsky D. Cellulitis: a review. JAMA. 2016 Jul 19;316(3):325-37. Abstract

Stevens DL, Bisno AL, Chambers HF, et al. Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America. Clin Infect Dis. 2014 Jul 15;59(2):e10-52.Full text  Abstract

American College of Radiology. ACR appropriateness criteria: suspected osteomyelitis, septic arthritis, or soft tissue infection (excluding spine and diabetic foot). 2022 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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