Resumen
Definición
Anamnesis y examen
Principales factores de diagnóstico
- prurito
- placas o pápulas violáceas de aspecto plano en la parte superior
- estrías de Wickham
- erosiones mucosales y red blanca en encaje
- alopecia cicatricial
- afectación de las uñas
Otros factores de diagnóstico
- pterigión dorsal
- antecedentes de hepatitis C (VHC)
Factores de riesgo
- hepatitis C (en algunas poblaciones de pacientes)
- polimorfismo -308 G/A en el gen de factor de necrosis tumoral (TNF) alfa
- vacunación contra la hepatitis B
- vacunación contra la gripe
- vacunación contra la enfermedad por coronavirus 2019 (COVID-19)
- estrés psicosocial
- alérgenos orales
- uso de determinados fármacos
Pruebas diagnósticas
Primeras pruebas diagnósticas para solicitar
- diagnóstico clínico
Pruebas diagnósticas que deben considerarse
- histopatología
- cribado de hepatitis C (VHC)
- inmunofluorescencia
Algoritmo de tratamiento
enfermedad cutánea
enfermedad en el cuero cabelludo
enfermedad de la cavidad oral
enfermedad genital
enfermedad ungueal
Colaboradores
Autores
Deepani Munidasa, MBBS, MD
Consultant Dermatologist
Department of Dermatology
Anuradhapura Teaching Hospital
Anuradhapura
Sri Lanka
Divulgaciones
DM declares that she has no competing interests.
Agradecimientos
Dr Deepani Munidasa would like to gratefully acknowledge Dr Susan Cooper, Dr Rebecca Dunn, Dr Julia S. Lehman, Dr Megha M. Tollefson, and Dr Lawrence E. Gibson, previous contributors to this topic.
Divulgaciones
SC is chair of the British Society for the Study of Vulval Disease and receives royalties for contributions to UpToDate. RD, JSL, MMT, and LEG declare that they have no competing interests.
Revisores por pares
Brian Swick, MD
Clinical Assistant Professor
University of Iowa College of Medicine
Iowa City
IA
Divulgaciones
BS declares that he has no competing interests.
David Cassarino, MD, PhD
Assistant Professor
Department of Pathology and Laboratory Medicine
University of California
Los Angeles
CA
Divulgaciones
DC declares that he has no competing interests.
Referências
Principais artigos
American College of Obstetricians and Gynecologists. Practice bulletin no. 224: diagnosis and management of vulvar skin disorders. Jul 2020 [internet publication].Texto completo Resumo
Edwards SK, Bates CM, Lewis F, et al. 2014 UK national guideline on the management of vulval conditions. Int J STD AIDS. 2015 Aug;26(9):611-24. Resumo
Ioannides D, Vakirlis E, Kemeny L, et al. European S1 guidelines on the management of lichen planus: a cooperation of the European Dermatology Forum with the European Academy of Dermatology and Venereology. J Eur Acad Dermatol Venereol. 2020 Jul;34(7):1403-14.Texto completo Resumo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
Diagnósticos diferenciais
- Liquen simple crónico
- Psoriasis
- Liquen plano pénfigo
Mais Diagnósticos diferenciaisDiretrizes
- 2021 European guideline for the management of vulval conditions
- British Association of Dermatologists and British Photodermatology Group guidelines for narrowband ultraviolet B phototherapy
Mais Diretrizes
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