小结
定义
病史和体格检查
关键诊断因素
- dolor torácico
- Factores de riesgo para enfermedades cardiovasculares
- sudoración marcada
- shock cardiógeno
- Insuficiencia cardíaca aguda
其他诊断因素
- náuseas y vómitos
- arritmias
- ruido cardíaco anormal
- dolor epigástrico
- disnea
- síncope
- dolor de espalda
危险因素
- tabaquismo
- hipertensión
- diabetes
- obesidad y fenotipo del síndrome metabólico
- comportamiento sedentario e inactividad física
- dislipidemia
- enfermedad renal crónica
- aterosclerosis (antecedentes de angina, infarto de miocardio, accidente cerebrovascular, accidente isquémico transitorio, enfermedad vascular periférica)
- antecedentes familiares de enfermedad arterial coronaria prematura
- edad >60 años
- consumo de cocaína
- depresión
- trombosis del stent o reestenosis
- apnea del sueño
- procedimientos quirúrgicos (incluidos períodos intraoperativos y postoperativos)
- migraña
- Resultados adversos del embarazo
诊断性检查
首要检查
- electrocardiograma (ECG)
- troponina de alta sensibilidad
- ecocardiografía
- radiografía de tórax
- hemograma completo
- urea, electrolitos y creatinina
- pruebas de función hepática
- glucemia
- proteína C-reactiva
需考虑的检查
- angiografía coronaria invasiva (ICA)
- lípidos
治疗流程
características de riesgo muy alto o alto riesgo (sospecha o confirmación de IMSEST)
sin características de alto riesgo (sospecha o confirmación de IMSEST)
después del IMSEST
撰稿人
专家顾问
Shrilla Banerjee, MD, FRCP
Consultant Interventional Cardiologist
East Surrey Hospital
Surrey and Sussex Healthcare NHS Trust
UK
利益声明
SB has received speaker fees for educational lectures (presentation content was her own) and meeting participation from Menarini, Edwards Lifesciences, Abbott Vascular, and Shockwave IVL. She has also participated in an Advisory Board for Sahajanand Medical Technologies Limited. SB has received travel sponsorship from Biosensors International to attend the PCR meeting in Paris in 2022. She has prepared a manuscript on coronary microvascular dysfunction for Abbott for Cardiovascular News (no royalties).
Adam Hartley, MBBS, BSc, MRCP
Wellcome Trust Clinical Research Fellow
Imperial College London
Specialist Registrar in Cardiology
Imperial College Healthcare NHS Trust
London
UK
利益声明
AH declares that he has no competing interests.
Acknowledgements
BMJ Best Practice would like to gratefully acknowledge the previous expert contributors, whose work has been retained in parts of the content:
Resham Baruah MBBS, BSc MRCP, PhD
Consultant Cardiologist
Chelsea and Westminster Hospital NHS Foundation Trust
Royal Brompton & Harefield NHS Foundation Trust
London
UK
Cody S Deen, MD
Assistant Professor of Medicine
Director of Cardiology
Hillsborough Hospital
University of North Carolina
Hillsborough
NC
利益声明
RB has received honoraria/speakers’ fees from Novartis and Boehringer Ingelheim. CSD was previously the Director of Cardiac Rehab for Chatham Hospital, which was financially set up as a consultancy relationship, until 2017. CSD has spoken (unpaid) at the Update in Cardiology and Update in Internal Medicine Conferences at UNC for the last 5 years. CSD has served as the PI for the Dal-GeneE (site now closed) and the ACCELERATE Trials at the University of North Carolina (trial now completed). Each trial required paid travel to an investigator meeting.
同行评议者
Gavin Galasko, BM, BCh, MA, DM (Oxon), FRCP
Consultant Interventional Cardiologist
Director of Research, Development and Innovation
Blackpool Teaching Hospitals NHS Foundation Trust
Blackpool
UK
利益声明
GG declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
参考文献
关键文献
Amsterdam EA, Wenger NK, Brindis RG, et al. 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014 Dec 23;64(24):e139-228.全文 摘要
Byrne RA, Rossello X, Coughlan JJ, et al. 2023 ESC guidelines for the management of acute coronary syndromes. Eur Heart J. 2023 Oct 12;44(38):3720-826.全文 摘要
National Institute for Health and Care Excellence. Acute coronary syndromes. Nov 2020 [internet publication].全文
National Institute for Health and Care Excellence. Recent-onset chest pain of suspected cardiac origin: assessment and diagnosis. Nov 2016 [internet publication].全文
参考文献
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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