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Cáncer estomacal

Последний просмотренный: 15 Jul 2025
Last updated: 13 Sep 2024

Резюме

Определение

Анамнез и осмотр

Ключевые диагностические факторы

  • presencia de factores de riesgo
  • dolor abdominal
  • pérdida de peso
  • linfadenopatía
Полная информация

Другие диагностические факторы

  • edad 50-70 años
  • sexo masculino
  • tabaquismo
  • antecedentes familiares
  • náuseas
  • disfagia
  • sangrado en el tracto gastrointestinal inferior
Полная информация

Факторы риска

  • anemia perniciosa
  • Helicobacter pylori
  • compuestos N-nitrosos
  • dieta con pocas frutas y verduras
  • dieta hipersódica
  • tabaquismo
  • antecedentes familiares
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • endoscopia del tracto gastrointestinal superior con biopsia
  • hemograma completo (HC)
  • perfil metabólico completo (PMC)
Полная информация

Исследования, проведение которых нужно рассмотреть

  • TC de tórax/abdomen/pelvis
  • ultrasonido endoscópico
  • laparoscopia
  • TEP/TC
Полная информация

Алгоритм лечения

Острый

localizado: apto para cirugía

localizada: no apta para la cirugía

enfermedad avanzada y metastásica

Составители

Авторы

Ahmed Abdelhakeem, MD

Fellow Physician

Division of Hematology and Oncology

Mayo Clinic - Mayo Clinic Comprehensive Cancer Center

Jacksonville

FL

Раскрытие информации

AA declares that he has no competing interests.

Mariela Blum Murphy, MD

Associate Professor

Department of GI Medical Oncology

University of Texas

MD Anderson Cancer Center

Houston

TX

Раскрытие информации

MBM declares that she has no competing interests.

Выражение благодарностей

Dr Ahmed Abdelhakeem and Dr Mariela Blum Murphy would like to gratefully acknowledge Dr Valerie Reed and Dr Prajnan Das, previous contributors to this topic.

Раскрытие информации

VR and PD declare that they have no competing interests.

Рецензенты

Theodore Hong, MD

Director

Gastrointestinal Radiation Oncology

Massachusetts General Hospital Cancer Center

Boston

MA

Раскрытие информации

TH declares that he has no competing interests.

Andreas Leodolter, MD

Head of Department

Department of Gastroenterology

Sana Klinikum

Remscheid

Germany

Раскрытие информации

AL declares that he has no competing interests.

Список литературы

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Основные статьи

National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: gastric cancer [internet publication].Полный текст

Lordick F, Carneiro F, Cascinu S, et al. Gastric cancer: ESMO clinical practice guideline for diagnosis, treatment and follow-up. Ann Oncol. 2022 Oct;33(10):1005-20.Полный текст  Аннотация

Songun I, Putter H, Kranenbarg EM, et al. Surgical treatment of gastric cancer: 15-year follow-up results of the randomised nationwide Dutch D1D2 trial. Lancet Oncol. 2010 May;11(5):439-49. Аннотация

Smalley SR, Benedetti JK, Haller DG, et al. Updated analysis of SWOG-directed intergroup study 0116: a phase III trial of adjuvant radiochemotherapy versus observation after curative gastric cancer resection. J Clin Oncol. 2012 Jul 1;30(19):2327-33. Аннотация

Cunningham D, Allum WH, Stenning SP, et al. Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer. N Engl J Med. 2006 Jul 6;355(1):11-20.Полный текст  Аннотация

Bang YJ, Van CE, Feyereislova A, et al; ToGA Trial Investigators. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet. 2010 Aug 28;376(9742):687-97. Аннотация

Статьи, указанные как источники

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