Resumen
Definición
Anamnesis y examen
Principales factores de diagnóstico
- presencia de factores de riesgo
- antecedentes familiares de cardiopatía coronaria o dislipidemia de inicio temprano en parientes de primer grado
- antecedentes de enfermedad cardiovascular
- consumo de grasas saturadas y ácidos grasos trans
- exceso de peso corporal (especialmente obesidad abdominal)
- xantelasmas
- xantomas tendinosos
Otros factores de diagnóstico
- arco senil de la córnea con inicio antes de los 45 años de edad
- xantomas tuberosos
Factores de riesgo
- resistencia a la insulina y diabetes mellitus tipo 2
- exceso de peso corporal (índice de masa corporal > 25 kg/m²)
- tabaquismo
- hipotiroidismo.
- hepatopatía colestásica
- síndrome nefrótico
- uso de ciertos medicamentos
Pruebas diagnósticas
Primeras pruebas diagnósticas para solicitar
- lipidograma
- hormona estimulante de la tiroides (TSH)
- lipoproteina (a)
Algoritmo de tratamiento
Colaboradores
Autores

Associate Professor of Medicine
Director Lipid Clinic Heart Institute (InCor)
University of Sao Paulo Medical School Hospital
Scientific Advisor
Hospital Israelita Albert Einstein
Sao Paulo
Brazil
Divulgaciones
RDS has received honoraria for consulting, speaker activities and research from Astra Zeneca, Amgen, Akcea, Biolab, Esperion, Kowa, Pfizer, Merck, Novo-Nordisk, and Sanofi/Regeneron.

Associate Professor of Medicine/Cardiology
Director
Lipid Clinic
Ciccarone Center for the Prevention of Cardiovascular Disease
Division of Cardiology, Department of Medicine
Johns Hopkins University School of Medicine
Baltimore
MD
Divulgaciones
SSM has received honoraria from the American College of Cardiology for educational activities. SSM is listed as a co-inventor on a pending patent filed by Johns Hopkins University for a novel method of LDL-cholesterol estimation. SSM received a charitable gift for the VLDL big data project from the David and June Trone Family Foundation, and has also received research support from the PJ Schafer Cardiovascular Research Fund, American Heart Association, Aetna Foundation, iHealth, Stanford MedX/Nokia, Google, and Apple. SSM has acted as a consultant for Abbott Nutrition, Pressed Juicery, Quest Diagnostics, Sanofi/Regeneron, Amgen, Novo Nordisk, Esperian, Akcea, and the Pew Institute.

Cardiovascular Fellow
Pollin Prevention Fellow
Ciccarone Center for the Prevention of Cardiovascular Disease
Division of Cardiology, Department of Medicine
Johns Hopkins University School of Medicine
Baltimore
MD
Divulgaciones
RC declares that he has no competing interests.
Dr Raul D. Santos, Dr Seth S. Martin, and Dr Rhanderson Cardoso would like to gratefully acknowledge Dr Martin Engelhardt and Dr Michael Miller, the previous contributors to this topic.
Divulgaciones
ME declares that he has no competing interests. MM has received research grant support and honoraria for lectures from AstraZeneca, Merck-Schering Plough, and Pfizer. MM has received consulting fees from Pfizer, Merck-Schering Plough, and Roche.
Revisores por pares
Assistant Professor of Medicine
Noninvasive Cardiology
MetroHealth Campus
Case Western Reserve University
Cleveland
OH
Divulgaciones
MLA declares that he has no competing interests.
Consultant/Senior Lecturer in Diabetes & Metabolism
The Royal Oldham Hospital & University of Manchester Cardiovascular Research Group Diabetes Centre
Royal Oldham Hospital
Oldham
UK
Divulgaciones
DB declares that he has no competing interests.
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