Última revisión: 22 Sept 2020
Última actualización: 15 Oct 2019

Resumen

Definición

Anamnesis y exploración física

Factores clave de diagnóstico

  • presencia de factores de riesgo
  • antecedentes familiares de cardiopatía coronaria o dislipidemia de inicio temprano en parientes de primer grado
  • antecedentes de enfermedad cardiovascular
  • consumo de grasas saturadas y ácidos grasos trans
  • exceso de peso corporal (especialmente obesidad abdominal)
  • xantelasmas
  • xantomas tendinosos

Otros factores para el diagnóstico

  • arco senil de la córnea con inicio antes de los 45 años de edad
  • xantomas tuberosos

Factores de riesgo

  • resistencia a la insulina y diabetes mellitus tipo 2
  • exceso de peso corporal (índice de masa corporal > 25 kg/m²)
  • tabaquismo
  • hipotiroidismo.
  • hepatopatía colestásica
  • síndrome nefrótico
  • uso de ciertos medicamentos

Pruebas diagnósticas

Primeras pruebas que solicitar

  • lipidograma
  • hormona estimulante de la tiroides (TSH)
  • lipoproteina (a)
Más primeras pruebas que solicitar

Algoritmo de tratamiento

Colaboradores

Raul D. Santos

Associate Professor of Medicine

Director Lipid Clinic Heart Institute (InCor)

University of Sao Paulo Medical School Hospital

Scientific Advisor

Hospital Israelita Albert Einstein

Sao Paulo

Brazil

Conflicto de intereses

RDS has received honoraria for consulting, speaker activities and research from Astra Zeneca, Amgen, Akcea, Biolab, Esperion, Kowa, Pfizer, Merck, Novo-Nordisk, and Sanofi/Regeneron.

Seth S. Martin

Associate Professor of Medicine/Cardiology

Director

Lipid Clinic

Ciccarone Center for the Prevention of Cardiovascular Disease

Division of Cardiology, Department of Medicine

Johns Hopkins University School of Medicine

Baltimore

MD

Conflicto de intereses

SSM has received honoraria from the American College of Cardiology for educational activities. SSM is listed as a co-inventor on a pending patent filed by Johns Hopkins University for a novel method of LDL-cholesterol estimation. SSM received a charitable gift for the VLDL big data project from the David and June Trone Family Foundation, and has also received research support from the PJ Schafer Cardiovascular Research Fund, American Heart Association, Aetna Foundation, iHealth, Stanford MedX/Nokia, Google, and Apple. SSM has acted as a consultant for Abbott Nutrition, Pressed Juicery, Quest Diagnostics, Sanofi/Regeneron, Amgen, Novo Nordisk, Esperian, Akcea, and the Pew Institute.

Rhanderson Cardoso

Cardiovascular Fellow

Pollin Prevention Fellow

Ciccarone Center for the Prevention of Cardiovascular Disease

Division of Cardiology, Department of Medicine

Johns Hopkins University School of Medicine

Baltimore

MD

Conflicto de intereses

RC declares that he has no competing interests.

Dr Raul D. Santos, Dr Seth S. Martin, and Dr Rhanderson Cardoso would like to gratefully acknowledge Dr Martin Engelhardt and Dr Michael Miller, the previous contributors to this topic.

Revisores paresVER TODO

Assistant Professor of Medicine

Noninvasive Cardiology

MetroHealth Campus

Case Western Reserve University

Cleveland

OH

Conflicto de intereses

MLA declares that he has no competing interests.

Consultant/Senior Lecturer in Diabetes & Metabolism

The Royal Oldham Hospital & University of Manchester Cardiovascular Research Group Diabetes Centre

Royal Oldham Hospital

Oldham

UK

Conflicto de intereses

DB declares that he has no competing interests.

El uso de este contenido está sujeto a nuestra cláusula de exención de responsabilidad