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Rabdomiólisis

Última revisão: 20 Ago 2025
Última atualização: 02 Nov 2022

Resumo

Определение

Анамнез и осмотр

Ключевые диагностические факторы

  • lesión por aplastamiento reciente
  • inmovilización prolongada
  • presencia de otros factores de riesgo
  • dolor o debilidad muscular
Полная информация

Другие диагностические факторы

  • malestar general
  • orina oscura
  • inflamación muscular
  • sensibilidad muscular
  • pulso periférico disminuido
  • llenado capilar prolongado
Полная информация

Факторы риска

  • traumatismo
  • alcohol
  • cocaína
  • anfetaminas
  • fenciclidina
  • narcóticos
  • diuréticos
  • estatinas
  • toxicidad por salicilatos
  • toxinas
  • inoculación de veneno
  • trastornos inflamatorios
  • hipoxia muscular
  • trastornos genéticos
  • trastornos metabólicos
  • infección
  • aumento de la temperatura corporal
  • antipsicóticos
Полная информация

Диагностические исследования

Исследования, которые показаны в первую очередь

  • nivel de creatina-cinasa sérica (CK)
  • electrolitos séricos
  • función renal
  • función hepática
  • hemograma completo (HC)
  • estudios de coagulación
  • tira reactiva de orina
  • análisis microscópico de orina
  • niveles de mioglobina
Полная информация

Исследования, проведение которых нужно рассмотреть

  • biopsia muscular
  • hormona estimulante de la tiroides
  • velocidad de sedimentación globular
  • anticuerpos antinucleares
  • cribado toxicológico
Полная информация

Алгоритм лечения

Острый

lesión por aplastamiento y/o creatina-cinasa >5 veces lo normal o >1000 UI/L

daño renal agudo refractario al tratamiento inicial

Составители

Авторы

Chinmay Patel, MD, FASN

Nephrology Specialist

East Texas Kidney Specialists

Longview

TX

Раскрытие информации

CP is an author of one reference cited in this topic.

Aditya Kadiyala, MD, MPH

Vice Chair

Department of Medicine

Division of Nephrology

University of Maryland

Charles Regional Medical Center

La Plata

MD

Раскрытие информации

AK declares that he has no competing interests.

Выражение благодарностей

Dr Chinmay Patel and Dr Aditya Kadiyala would like to gratefully acknowledge Dr Mark Shapiro, Dr Courtney Sommer, and Dr Robert D. Mathis, previous contributors to this topic.

Раскрытие информации

MS is an author of references cited in this topic. CS and RDM declare that they have no competing interests.

Рецензенты

Timothy Albertson, MD, PhD, MPH

Chief

Division of Pulmonary and Critical Care Medicine

University of California, Davis

Sacramento

CA

Раскрытие информации

TA declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

Список литературы

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

Основные статьи

Kodadek L, Carmichael Ii SP, Seshadri A, et al. Rhabdomyolysis: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document. Trauma Surg Acute Care Open. 2022;7(1):e000836.Полный текст  Аннотация

The Renal Association (UK). Clinical practice guideline: acute kidney injury (AKI). Aug 2019 [internet publication].Полный текст

Sawhney JS, Kasotakis G, Goldenberg A, et al. Management of rhabdomyolysis: a practice management guideline from the Eastern Association for the Surgery of Trauma. Am J Surg. 2022 Jul;224(1 pt a):196-204.Полный текст  Аннотация

Статьи, указанные как источники

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
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