Summary
Definition
History and exam
Key diagnostic factors
- presencia de factores de riesgo
- mujeres en edad reproductiva
- menstruación irregular
- infertilidad
- hirsutismo
Other diagnostic factors
- acné
- sobrepeso u obesidad
- hipertensión
- caída del pelo del cuero cabelludo
- piel grasosa o sudoración excesiva
- acantosis pigmentaria
Risk factors
- antecedentes familiares del síndrome del ovario poliquístico (SOPQ)
- adrenarquía prematura
- obesidad
- bajo peso al nacer
- exposición del feto a los andrógenos
- disruptores endocrinos ambientales
Diagnostic tests
1st tests to order
- 17-hidroxiprogesterona sérica
- prolactina sérica
- hormona estimulante de la tiroides en suero
- prueba de tolerancia a la glucosa oral
- perfil lipídico en ayunas
Tests to consider
- niveles séricos de testosterona libre y total
- sulfato de deshidroepiandrosterona (DHEAS) en sangre
- androstenediona sérica
- ultrasonido pélvico
- hormona antimulleriana en suero
- monitorización de la temperatura corporal basal
- medición de progesterona en la fase lútea
- hormona luteinizante (LH) y hormona foliculoestimulante (FSH) séricas
- hemoglobina A1c o glucosa plasmática en ayunas
Treatment algorithm
con infertilidad cuando se desea fertilidad
sin deseo actual de fertilidad
Contributors
Authors
Mark O. Goodarzi, MD, PhD
Division of Endocrinology, Diabetes & Metabolism
Eris M. Field Chair in Diabetes Research
Professor of Medicine
Cedars-Sinai Medical Center
Los Angeles
CA
Disclosures
MOG has been reimbursed for one-time participation in an advisory board for Nestle Health Science on the topic of exocrine pancreatic dysfunction. MOG is an author of a number of references cited in this topic.
Peer reviewers
Antoni Duleba, MD
Professor
Department of Obstetrics and Gynecology
University of California Davis
Sacramento
CA
Disclosures
AD declares that he has no competing interests.
Richard S. Legro, MD
Professor
Department of Obstetrics and Gynecology
Penn State Hershey College of Medicine
Hershey
PA
Disclosures
RSL has been reimbursed by Serono for attending a medical conference and received a lecture fee, and has consulted for Ferring. He has received research funding from the NIH, the Commonwealth of Pennsylvania, and Parke Davis. He is an author of a number of references cited in this topic.
Cornelis B. (Nils) Lambalk, MD, PhD
Gynaecologist/Fertility Specialist
Division of Reproductive Medicine
Department of Obstetrics and Gynaecology
VU University Medical Centre
Amsterdam
The Netherlands
Disclosures
CBL declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
References
Key articles
Azziz R, Carmina E, Chen Z, et al. Polycystic ovary syndrome. Nat Rev Dis Primers. 2016 Aug 11;2:16057. Abstract
Teede HJ, Tay CT, Laven JJE, et al. Recommendations from the 2023 international evidence-based guideline for the assessment and management of polycystic ovary syndrome. J Clin Endocrinol Metab. 2023 Sep 18;108(10):2447-69.Full text Abstract
Reference articles
A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.
Differentials
- Deficiencia de 21-hidroxilasa
- Disfunción tiroidea
- Hiperprolactinemia
More DifferentialsGuidelines
- International evidence-based guideline for the assessment and management of polycystic ovary syndrome
- Practice bulletin: polycystic ovary syndrome
More GuidelinesPatient information
Síndrome del ovario poliquístico: ¿qué es?
Síndrome del ovario poliquístico: preguntas para formularle al médico
More Patient information
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