Summary
Определение
Анамнез и осмотр
Ключевые диагностические факторы
- presencia de factores de riesgo
Другие диагностические факторы
- disnea de esfuerzo
- tos
- exploración física de tórax normal
- crepitantes durante la auscultación pulmonar
- opresión en el pecho o sibilancias
- espiración prolongada y sibilancias en la auscultación pulmonar
- áreas de matidez en la percusión torácica
- cianosis
- tórax en tonel
- hemoptisis, fiebre o sudores nocturnos
- hipocratismo digital de las manos y los pies
- pérdida de peso
- signos de artritis reumatoide o esclerodermia
- signos de insuficiencia renal (p. ej., aumento de peso, edema, hipertensión)
Факторы риска
- exposición laboral a la sílice
- exposición laboral al carbón
- exposición laboral al berilio
- dosis de carbón o sílice inhalados de alta acumulación
- tabaquismo
- ácido glutámico en la posición 69 de la cadena B1 de la molécula HLA-DP (enfermedad crónica por berilio)
- dosis de berilio inhalado de alta acumulación
Диагностические исследования
Исследования, которые показаны в первую очередь
- radiografía de tórax (posteroanterior y lateral)
- espirometría
- prueba de proliferación de linfocitos de berilio (BeLPT)
Исследования, проведение которых нужно рассмотреть
- biopsia broncoscópica y/o lavado
- exploración de tórax por tomografía computarizada (TC) de alta resolución (HRCT)
- saturación de oxígeno
- gasometría arterial (GSA)
- biopsia pulmonar
- prueba de la tuberculosis (TB)
Алгоритм лечения
proteinosis alveolar secundaria aguda (silicosis aguda)
beriliosis aguda
silicosis crónica, pulmón de los trabajadores del carbón o beriliosis crónica
Составители
Авторы
Kenneth D. Rosenman, MD
Professor of Medicine
Division of Occupational and Environmental Medicine
Michigan State University
East Lansing
MI
Раскрытие информации
KDR declares no competing interests.
Рецензенты
Ware G. Kuschner, MD
Associate Professor of Medicine
Stanford University
Staff Physician
US Department of Veterans Affairs
Palo Alto Health Care System
Palo Alto
CA
Раскрытие информации
WGK declares that he has no competing interests.
Harman Paintal, MBBS
Division of Pulmonary and Critical Care Medicine
Veterans Affairs Palo Alto Health Care System (VAPAHCS)
Palo Alto
CA
Раскрытие информации
HP declares that he has no competing interests.
Francis Thien, MD, FRACP, FCCP
Professor
Box Hill Hospital and Monash University
Victoria
Australia
Declarações
FT declares that he has no competing interests.
Edward L. Petsonk, MD
Professor of Medicine
Section of Pulmonary and Critical Care Medicine
West Virginia University School of Medicine
Morgantown
WV
Declarações
ELP declares that he has no competing interests.
Christopher M. Barber, BM, BS, BMedSci, FRCP, MD, AFOM
Respiratory Consultant
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield
UK
Declarações
CMB declares that he has no competing interests.
Carl J. Reynolds, MBBS, MRCP, BSc, MSc, PhD, DPMSA
Respiratory Consultant
Honorary Senior Clinical Lecturer
North Middlesex University Hospital
Imperial College London
UK
Declarações
CJR declares that he has no competing interests.
Peer reviewer acknowledgements
BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.
Disclosures
Peer reviewer affiliations and disclosures pertain to the time of the review.
Referências
Principais artigos
Balmes JR, Abraham JL, Dweik RA, et al. An official American Thoracic Society statement: diagnosis and management of beryllium sensitivity and chronic beryllium disease. Am J Respir Crit Care Med. 2014 Nov 15;190(10):e34-59.Texto completo Resumo
American College of Radiology. ACR Appropriateness Criteria: occupational lung diseases. 2019 [internet publication].Texto completo
National Institute for Occupational Safety and Health. Health effects of occupational exposure to respirable crystalline silica. Apr 2002 [internet publication].Texto completo
International Labour Office. Guidelines for the use of the ILO international classification of radiographs of pneumoconioses, revised edition. 2022 [internet publication].Texto completo
US Occupational Safety and Health Administration (OSHA). Final rule to protect workers from occupational exposure to respirable crystalline silica. Appendix B to §1926.1153 construction standard - medical surveillance guidelines. Jun 2016 [internet publication].Texto completo
Artigos de referência
Uma lista completa das fontes referenciadas neste tópico está disponível para os usuários com acesso total ao BMJ Best Practice.
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