Last reviewed: 4 Feb 2021
Last updated: 12 Feb 2020
Summary
Definition
History and exam
Other diagnostic factors
- absence of thyroid enlargement/nodules
- absence of central nervous system (CNS) signs
- dry mucous membranes
- postural dizziness
- tachycardia
- hypotension
- ketotic breath
Risk factors
- family history of hyperemesis gravidarum
- previous history of NVP
- multiple gestation or increased placental mass
- gestational trophoblastic disease
- other causes of increased placental mass
- female fetus
- history of motion sickness
- history of migraine headache
Diagnostic investigations
1st investigations to order
- complete blood count
- basic metabolic panel
- serum liver function tests
- serum BUN and creatinine
- serum thyroid-stimulating hormone (TSH) and free thyroxine (T4)
- urinalysis
- urine or serum ketones
- fetal ultrasound with nuchal translucency
- serum analytes
- Helicobacter pylori breath test
Investigations to consider
- urine culture
- serum amylase and lipase
- abdominal ultrasound
- renal ultrasound
- cranial CT or MRI
Treatment algorithm
Contributors
Authors
Associate Professor
Family Medicine
Uniformed Services University of Health Sciences
Bethesda
MD
Disclosures
JDQ declares that he has no competing interests.
Peer reviewers
Faculty Physician
Family Medicine Residency
Naval Hospital Jacksonville
FL
Disclosures
SJ declares that she has no competing interests.
Assistant Professor
Head of Department of Obstetrics and Gynecology
Mosul College of Medicine
Mosul
Iraq
Disclosures
YTJ declares that he has no competing interests.
Associate Director
Department of Obstetrics and Gynecology
Florida Hospital
Orlando
FL
Disclosures
DAH declares that he has no competing interests.
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