Evaluation of tremor

Last reviewed: 9 Apr 2025
Last updated: 09 Nov 2022

Summary

Differentials

Common

  • Parkinson disease (PD)
  • Dementia with Lewy bodies
  • Enhanced physiologic tremor
  • Hypoglycemia (enhanced physiologic tremor)
  • Thyrotoxicosis (enhanced physiologic tremor)
  • Alcohol withdrawal (enhanced physiologic tremor)
  • Essential tremor or essential tremor plus
  • Drug-induced tremor
Full details

Uncommon

  • Multiple system atrophy
  • Progressive supranuclear palsy
  • Cortical basal degeneration
  • Toxin-induced tremor
  • Postencephalitic parkinsonism
  • Pheochromocytoma (enhanced physiologic tremor)
  • Cerebellar tremor (multiple sclerosis, trauma, or stroke)
  • Fragile X tremor ataxia syndrome
  • Orthostatic tremor
  • Primary writing tremor
  • Dystonic tremor
  • Wilson disease
  • Rubral tremor
  • Functional (psychogenic) tremor
Full details

Contributors

Authors

Kelvin L. Chou, MD
Kelvin L. Chou

Professor of Neurology and Neurosurgery

University of Michigan

Ann Arbor

MI

Disclosures

KLC serves on the medical advisory board (unpaid position) for the International Essential Tremor Foundation.

Praveen Dayalu, MD
Praveen Dayalu

Associate Professor of Neurology

University of Michigan

Ann Arbor

MI

Disclosures

PD declares that he has no competing interests.

Peer reviewers

Aparna Wagle Shukla, null

Professor

Movement Disorders Division

Department of Neurology

University of Florida

Gainesville

FL

Disclosures

WS has been reimbursed by Merz, ES therapeutics, Sage, Jazz, and Acadia.

Paul Greene, MD

Associate Professor of Clinical Neurology

Yale School of Medicine

New Haven

CT

Disclosures

PG declares that he has no competing interests.

References

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Key articles

Zesiewicz TA, Hauser RA. Phenomenology and treatment of tremor disorders. Neurol Clin. 2001;19:651-680. Abstract

Bhatia KP, Bain P, Bajaj N, et al. Consensus Statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society. Mov Disord. 2018 Jan;33(1):75-87.Full text  Abstract

Zesiewicz TA, Elble RJ, Louis ED, et al. Evidence-based guideline update: treatment of essential tremor: report of the Quality Standards subcommittee of the American Academy of Neurology. Neurology. 2011 Nov 8;77(19):1752-5.Full text  Abstract

American College of Radiology. Appropriateness Criteria: movement disorders and neurodegenerative diseases. 2020 [internet publication].Full text

Reference articles

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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