Evaluation of tremor

Last reviewed: 12 Dec 2025
Last updated: 22 Oct 2025

Summary

Differentials

Common

  • Parkinson disease (PD)
  • Dementia with Lewy bodies
  • Enhanced physiologic tremor
  • Hypoglycemia (enhanced physiologic tremor)
  • Thyrotoxicosis (enhanced physiologic tremor)
  • Alcohol withdrawal (enhanced physiologic tremor)
  • Essential tremor or essential tremor plus
  • Drug-induced tremor
Full details

Uncommon

  • Multiple system atrophy
  • Progressive supranuclear palsy (PSP)
  • Cortico basal syndrome
  • Toxin-induced tremor
  • Pheochromocytoma (enhanced physiologic tremor)
  • Cerebellar tremor (multiple sclerosis, trauma, or stroke)
  • Fragile X tremor ataxia syndrome
  • Orthostatic tremor
  • Primary writing tremor
  • Dystonic tremor
  • Wilson disease
  • Holmes tremor (rubral or midbrain tremor)
  • Functional tremor
Full details

Contributors

Authors

Camilla Kilbane, MD, FAAN

Associate Professor Neurology

Center Director Parkinson’s Disease and Movement disorder Center

Institution University Hospitals Cleveland Medical Center / Case Western Reserve University

Cleveland

OH

Disclosures

CK has served as a consultant for Medtronic, including participation on the Data Safety Monitoring Board (DSMB) for the ADAPT-PD trial. CK has participated in the speakers bureau for Teva Pharmaceuticals and has served as an expert witness in one legal case.

Acknowledgements

Dr Camilla Kilbane would like to gratefully acknowledge Professor Kelvin L. Chou and Dr Praveen Dayalui, previous contributors to this topic.

Disclosures

KLC serves as a consultant for Abbott (DBS manufacturer). PD declares that he has no competing interests.

Peer reviewers

Aparna Wagle Shukla, null

Professor

Movement Disorders Division

Department of Neurology

University of Florida

Gainesville

FL

Disclosures

WS has been reimbursed by Merz, ES therapeutics, Sage, Jazz, and Acadia.

Paul Greene, MD

Associate Professor of Clinical Neurology

Yale School of Medicine

New Haven

CT

Declarações

PG declares that he has no competing interests.

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Referências

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Principais artigos

Bhatia KP, Bain P, Bajaj N, et al. Consensus statement on the classification of tremors. from the task force on tremor of the International Parkinson and Movement Disorder Society. Mov Disord. 2018 Jan;33(1):75-87.Texto completo  Resumo

Shanker V. Essential tremor: diagnosis and management. BMJ. 2019 Aug 5;366:l4485.Texto completo  Resumo

American College of Radiology. ACR appropriateness criteria: movement disorders and neurodegenerative diseases. 2019 [internet publication].Texto completo

Artigos de referência

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