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最后审阅: 2 Dec 2025
最后更新: 15 Apr 2025

小结

定义

病史和体格检查

关键诊断因素

  • identification of the snake
  • local redness, swelling, tenderness, and pain at wound site
  • blurred or double vision
  • shortness of breath
  • difficulty swallowing
  • hypotension
  • tachypnea
  • tachycardia
  • puncture marks, fang marks
  • bulbar weakness/paralysis
  • stridor
  • hemorrhage
  • quadriplegia/locked-in syndrome
完整详情

其他诊断因素

  • nausea and vomiting
  • malaise, generalized weakness or dizziness
  • perioral tingling or numbness
  • urticaria
  • tremors
完整详情

危险因素

  • male sex
  • alcohol consumption
  • intentional snake encounter
完整详情

诊断性检查

首要检查

  • prothrombin time, PTT, fibrinogen, and D-dimer
  • CBC
  • electrolytes, BUN, and creatinine
  • arterial blood gas
  • creatine kinase (CK)
  • lactate
  • urinalysis
  • ECG
  • chest x-ray
  • wound x-ray
  • negative inspiratory force (NIF) test
完整详情

需考虑的检查

  • CT/MRI
  • compartment pressure
  • central venous line with central venous pressure (CVP) transduction
  • arterial line with pressure transduction
完整详情

治疗流程

初步治疗

presumed snakebite

急症处理

confirmed snakebite

撰稿人

作者

David Vearrier, MD, MPH, FAAEM, FACMT, FAACT
David Vearrier

Professor of Emergency Medicine

Division of Medical Toxicology

Department of Emergency Medicine

Program Director, Medical Toxicology Fellowship

Associate Program Director, Preventive Medicine Residency

Co-Director, Student and Employee Health

Department of Preventive Medicine

University of Mississippi Medical Center

Jackson

MS

利益声明

DV declares that he has no competing interests.

鸣谢

Prof. David Vearrier would like to gratefully acknowledge Prof. Michael Greenberg, previous contributor to this topic. MG declared that he had no competing interests.

同行评议者

Scott Phillips, MD

Associate Clinical Professor of Medicine

Department of Clinical Pharmacology and Toxicology

University of Colorado

Health Science Center

Denver

CO

利益声明

SP has a professional relationship with Michael Greenberg, one of the original contributors to this topic. They are partners in a private consulting company. SP does not receive money from him, nor does he receive money from SP.

Donna Seger, MD

Medical Director TN Poison Center

Associate Professor of Medicine and Emergency Medicine

Vanderbilt University Medical Center

Nashville

TN

利益声明

DS declares that she has no competing interests.

Senanayake Kularatne, MBBS, MD, MRCP, FRCP, FCCP

Professor

Department of Medicine

Peredeniya University

Sri Lanka

利益声明

SK declares that he has no competing interests.

Peer reviewer acknowledgements

BMJ Best Practice topics are updated on a rolling basis in line with developments in evidence and guidance. The peer reviewers listed here have reviewed the content at least once during the history of the topic.

Disclosures

Peer reviewer affiliations and disclosures pertain to the time of the review.

参考文献

Our in-house evidence and editorial teams collaborate with international expert contributors and peer reviewers to ensure that we provide access to the most clinically relevant information possible.

关键文献

Kanaan NC, Ray J, Stewart M, et al. Wilderness Medical Society practice guidelines for the treatment of pitviper envenomations in the United States and Canada. Wilderness Environ Med. 2015 Dec;26(4):472-87.全文  摘要

Hewett Brumberg EK, Douma MJ, Alibertis K, et al. 2024 American Heart Association and American Red Cross guidelines for first aid. Circulation. 2024 Dec 10;150(24):e519-79.全文  摘要

Lavonas EJ, Ruha AM, Banner W, et al. Unified treatment algorithm for the management of crotaline snakebite in the United States: results of an evidence-informed consensus workshop. BMC Emerg Med. 2011 Feb 3;11:2.全文  摘要

参考文献

A full list of sources referenced in this topic is available to users with access to all of BMJ Best Practice.

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