When viewing this topic in a different language, you may notice some differences in the way the content is structured, but it still reflects the latest evidence-based guidance.

Snake bites

Last reviewed: 21 Oct 2024
Last updated: 05 Apr 2023

Summary

Definition

History and exam

Key diagnostic factors

  • identification of the snake
  • local redness, swelling, tenderness, and pain at wound site
  • blurred or double vision
  • shortness of breath
  • difficulty swallowing
  • hypotension
  • tachypnea
  • tachycardia
  • puncture marks, fang marks
  • bulbar weakness/paralysis
  • stridor
  • hemorrhage
  • quadriplegia/locked-in syndrome
Full details

Other diagnostic factors

  • nausea and vomiting
  • malaise, generalized weakness or dizziness
  • perioral tingling or numbness
  • urticaria
  • tremors
Full details

Risk factors

  • male sex
  • alcohol consumption
  • intentional snake encounter
Full details

Diagnostic tests

1st tests to order

  • prothrombin time, PTT, fibrinogen, and D-dimer
  • CBC
  • electrolytes, BUN, and creatinine
  • arterial blood gas
  • creatine kinase (CK)
  • lactate
  • urinalysis
  • ECG
  • chest x-ray
  • wound x-ray
  • negative inspiratory force (NIF) test
Full details

Tests to consider

  • CT/MRI
  • compartment pressure
  • central venous line with central venous pressure (CVP) transduction
  • arterial line with pressure transduction
Full details

Treatment algorithm

INITIAL

presumed snakebite

ACUTE

confirmed snakebite

Contributors

Authors

David Vearrier, MD, MPH, FAAEM, FACMT, FAACT
David Vearrier

Professor of Emergency Medicine

Division of Medical Toxicology

Department of Emergency Medicine

Associate Program Director, Preventive Medicine Residency

Co-Director, Student and Employee Health

Department of Preventive Medicine

University of Mississippi Medical Center

Jackson

MS

Disclosures

DV declares that he has no competing interests.

Acknowledgements

Prof. David Vearrier would like to gratefully acknowledge Prof. Michael Greenberg, previous contributor to this topic. MG declared that he had no competing interests.

Peer reviewers

Scott Phillips, MD

Associate Clinical Professor of Medicine

Department of Clinical Pharmacology and Toxicology

University of Colorado

Health Science Center

Denver

CO

Disclosures

SP has a professional relationship with Michael Greenberg, one of the original contributors to this topic. They are partners in a private consulting company. SP does not receive money from him, nor does he receive money from SP.

Donna Seger, MD

Medical Director TN Poison Center

Associate Professor of Medicine and Emergency Medicine

Vanderbilt University Medical Center

Nashville

TN

Disclosures

DS declares that she has no competing interests.

Senanayake Kularatne, MBBS, MD, MRCP, FRCP, FCCP

Professor

Department of Medicine

Peredeniya University

Sri Lanka

Disclosures

SK declares that he has no competing interests.

  • Snake bites images
  • Differentials

    • Anaphylaxis
    More Differentials
  • Guidelines

    • Part 15: First aid. 2015 American Heart Association and American Red Cross guidelines update for first aid
    • Wilderness Medical Society practice guidelines for the treatment of pitviper envenomations in the US and Canada
    More Guidelines
  • padlock-lockedLog in or subscribe to access all of BMJ Best Practice

Use of this content is subject to our disclaimer