Non-cholera Vibrio infections

Vibrio vulnificus is the most virulent and can rapidly produce fatal septic shock in immunocompromised patients or those with underlying liver disease.

The diagnosis is based on blood, wound, and/or stool cultures.

Treatment consists of intravenous antibiotic therapy with two agents for those with sepsis or severe systemic infection. Patients with necrotizing skin/soft-tissue infection also require early aggressive debridement of the infected tissue. Localized skin/soft-tissue wound infections are managed with oral antibiotics and close observation.

Gastroenteritis syndromes are treated with rehydration. Oral antibiotics are indicated if diarrhea persists >5 days.

Prognosis varies with the host's underlying comorbidity and the clinical presentation of the infection.

Non-cholera Vibrio infections are infections caused by Vibrio species other than V cholerae. Vibrio infections are most often associated with consumption of raw or undercooked shellfish, or traumatic exposure to sea or brackish water. They are characterized by diarrhea and vomiting, sepsis, and/or skin/soft-tissue infections.